[HTML][HTML] Methylation-induced repression—belts, braces, and chromatin
AP Bird, AP Wolffe - Cell, 1999 - cell.com
). It may also contribute to immobilization of mammalian transposons, suppression of
transcriptional noise, and the control of tissue-specific gene expression, but decisive …
transcriptional noise, and the control of tissue-specific gene expression, but decisive …
DNA methylation: the nuts and bolts of repression
TB Miranda, PA Jones - Journal of cellular physiology, 2007 - Wiley Online Library
DNA methylation is an epigenetic modification which plays an important role in chromatin
organization and gene expression. DNA methylation can silence genes and repetitive …
organization and gene expression. DNA methylation can silence genes and repetitive …
[HTML][HTML] Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
PL Jones, GJC Veenstra, PA Wade, D Vermaak… - Nature …, 1998 - nature.com
CpG methylation in vertebrates correlates with alterations in chromatin structure and gene
silencing 1, 2, 3, 4. Differences in DNA-methylation status are associated with imprinting …
silencing 1, 2, 3, 4. Differences in DNA-methylation status are associated with imprinting …
[HTML][HTML] Periodic DNA methylation in maize nucleosomes and demethylation by environmental stress
N Steward, M Ito, Y Yamaguchi, N Koizumi… - Journal of Biological …, 2002 - ASBMB
When maize seedlings were exposed to cold stress, a genome-wide demethylation occurred
in root tissues. Screening of genomic DNA identified one particular fragment that was …
in root tissues. Screening of genomic DNA identified one particular fragment that was …
[HTML][HTML] DNA methylation and histone H1 jointly repress transposable elements and aberrant intragenic transcripts
DNA methylation and histone H1 mediate transcriptional silencing of genes and
transposable elements, but how they interact is unclear. In plants and animals with mosaic …
transposable elements, but how they interact is unclear. In plants and animals with mosaic …
[HTML][HTML] Whole genome DNA methylation: beyond genes silencing
The combination of DNA bisulfite treatment with high-throughput sequencing technologies
has enabled investigation of genome-wide DNA methylation at near base pair level …
has enabled investigation of genome-wide DNA methylation at near base pair level …
Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A
RDW Kelly, A Mahmud, M McKenzie… - Nucleic acids …, 2012 - academic.oup.com
DNA methylation is an essential mechanism controlling gene expression during
differentiation and development. We investigated the epigenetic regulation of the nuclear …
differentiation and development. We investigated the epigenetic regulation of the nuclear …
Impact of alternative DNA structures on DNA damage, DNA repair, and genetic instability
G Wang, KM Vasquez - DNA repair, 2014 - Elsevier
Repetitive genomic sequences can adopt a number of alternative DNA structures that differ
from the canonical B-form duplex (ie non-B DNA). These non-B DNA-forming sequences …
from the canonical B-form duplex (ie non-B DNA). These non-B DNA-forming sequences …
[HTML][HTML] The cell-specific expression of endothelial nitric-oxide synthase: a role for DNA methylation
The basis for the endothelial cell-restricted expression of endothelial nitric-oxide synthase
(eNOS) is not known. While transgenic promoter/reporter mice demonstrated endothelium …
(eNOS) is not known. While transgenic promoter/reporter mice demonstrated endothelium …
[HTML][HTML] DDM1 and Lsh remodelers allow methylation of DNA wrapped in nucleosomes
DB Lyons, D Zilberman - Elife, 2017 - elifesciences.org
Cytosine methylation regulates essential genome functions across eukaryotes, but the
fundamental question of whether nucleosomal or naked DNA is the preferred substrate of …
fundamental question of whether nucleosomal or naked DNA is the preferred substrate of …