Increasing numbers of studies implicate abnormal DNA methylation in cancer and many non-
malignant diseases. This is consistent with numerous findings about differentiation …

Memory, defined as the storage and use of learned information in the brain, is necessary to
modulate behavior and critical for animals to adapt to their environments and survive …

In the past few decades, the field of neuroepigenetics has investigated how the brain
encodes information to form long-lasting memories that lead to stable changes in behaviour …

Pain is an unpleasant but essential-to-life sensation, usually resulting from tissue damage.
When pain persists long after the injury has resolved, it becomes pathological. The precise …

Memories are encoded by memory traces or engrams, represented within subsets of
neurons that are synchronously activated during learning. However, the molecular …

Previously, we reported that long-term memory (LTM) in Aplysia can be reinstated by
truncated (partial) training following its disruption by reconsolidation blockade and inhibition …

A single event can cause a life-long memory. Memories physically reside in neurons, and
changes in neuronal gene expression are considered to be central to memory. Early models …

The neuronal epigenome is highly sensitive to external events and its function is vital for
producing stable behavioral outcomes, such as the formation of long-lasting memories. The …

Over the last decade, an increasing number of reports underscored the importance of
epigenetic regulations in brain plasticity. Epigenetic elements such as readers, writers and …

Exposure to anaesthetic drugs during the fetal or neonatal period induces widespread
neuronal apoptosis in the brains of rodents and non-human primates. Hundreds of …