Pathophysiology and epidemiology of abdominal aortic aneurysms

IM Nordon, RJ Hinchliffe, IM Loftus… - Nature reviews …, 2011 - nature.com
Abdominal aortic aneurysms (AAAs) are found in up to 8% of men aged> 65 years, yet
usually remain asymptomatic until they rupture. Rupture of an AAA and its associated …

[HTML][HTML] AAA revisited: a comprehensive review of risk factors, management, and hallmarks of pathogenesis

V Kessler, J Klopf, W Eilenberg, C Neumayer… - Biomedicines, 2022 - mdpi.com
Despite declining incidence and mortality rates in many countries, the abdominal aortic
aneurysm (AAA) continues to represent a life-threatening cardiovascular condition with an …

[HTML][HTML] Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1· 9 million people

AD Shah, C Langenberg, E Rapsomaniki… - The lancet Diabetes & …, 2015 - thelancet.com
Background The contemporary associations of type 2 diabetes with a wide range of incident
cardiovascular diseases have not been compared. We aimed to study associations between …

[HTML][HTML] Risk factors for thoracic aortic dissection

Z Zhou, AC Cecchi, SK Prakash, DM Milewicz - Genes, 2022 - mdpi.com
Thoracic aortic aneurysms involving the root and/or the ascending aorta enlarge over time
until an acute tear in the intimal layer leads to a highly fatal condition, an acute aortic …

Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection

S Debette, Y Kamatani, TM Metso, M Kloss… - Nature …, 2015 - nature.com
Cervical artery dissection (CeAD), a mural hematoma in a carotid or vertebral artery, is a
major cause of ischemic stroke in young adults although relatively uncommon in the general …

[HTML][HTML] Comparison of surveillance versus aortic endografting for small aneurysm repair (CAESAR): results from a randomised trial

P Cao, P De Rango, F Verzini, G Parlani… - European Journal of …, 2011 - Elsevier
BACKGROUND: Randomised trials have failed to demonstrate benefit from early surgical
repair of small abdominal aortic aneurysm (AAA) compared with surveillance. This study …

Aneurysm global epidemiology study: public health measures can further reduce abdominal aortic aneurysm mortality

D Sidloff, P Stather, N Dattani, M Bown, J Thompson… - Circulation, 2014 - Am Heart Assoc
Background—Contemporary data from Western populations suggest steep declines in
abdominal aortic aneurysm (AAA) mortality; however, international trends are unclear. This …

[HTML][HTML] Diabetes and abdominal aortic aneurysms

P De Rango, L Farchioni, B Fiorucci, M Lenti - European Journal of …, 2014 - Elsevier
Epidemiologic evidence suggests that patients with diabetes may have a lower incidence of
abdominal aortic aneurysm (AAA); however, the link between diabetes and AAA …

Growth and remodeling of load-bearing biological soft tissues

CJ Cyron, JD Humphrey - Meccanica, 2017 - Springer
The past two decades reveal a growing role of continuum biomechanics in understanding
homeostasis, adaptation, and disease progression in soft tissues. In this paper, we briefly …

Epidemiology and contemporary management of abdominal aortic aneurysms

BW Ullery, RL Hallett, D Fleischmann - Abdominal Radiology, 2018 - Springer
Abdominal aortic aneurysm (AAA) is most commonly defined as a maximal diameter of the
abdominal aorta in excess of 3 cm in either anterior-posterior or transverse planes or …