Epigenetics has enriched human disease studies by adding new interpretations to disease
features that cannot be explained by genetic and environmental factors. However …

Pancreatic cancer (PC) has a very high mortality rate globally. Despite ongoing efforts, its
prognosis has not improved significantly over the last two decades. Thus, further …

The integration of circadian and metabolic signals is essential for maintaining robust
circadian rhythms and ensuring efficient metabolism and energy use. Using Drosophila as …

The mammalian molecular clock comprises a complex network of transcriptional programs
that integrates environmental signals with physiological pathways in a tissue-specific …

Background & objectives Hepatocellular carcinoma (HCC) is the second leading cause of
cancer death worldwide. Several types of chronic liver disease predispose to HCC, and …

Particulate matter≤ 2.5 μm (PM 2.5) air pollution is a leading environmental risk factor
contributing disproportionately to the global burden of non-communicable disease. We …

Ageing is a multifactorial physiological manifestation that occurs inexorably and gradually in
all forms of life. This process is linked to the decay of homeostasis due to the progressive …

The circadian clock is regulated at the molecular level by feedback circuits of a group of
genes known as" clock genes", which establish a mechanism that controls circadian cellular …

Circadian rhythmicity governs a remarkable array of fundamental biological functions and is
mediated by cyclical transcriptomic and proteomic activities. Epigenetic factors are also …

Rhythmic oscillations of physiological processes depend on integrating the circadian clock
and diurnal environment. DNA methylation is epigenetically responsive to daily rhythms, as …