Tremendous advances in our understanding of the thrombotic microangiopathies (TMAs)
have revealed distinct disease mechanisms within this heterogeneous group of diseases. As …

Hemolytic uremic syndrome (HUS) is a triad of microangiopathic hemolytic anemia,
thrombocytopenia, and acute renal failure. The atypical form of HUS is a disease …

Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia,
thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shiga-toxin …

Introduction Among various lupus renal vascular changes, thrombotic microangiopathy
(TMA) presented with the most severe clinical manifestations and high mortality. The …

Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy
that associates, in 70% of cases, with genetic or acquired disorders leading to dysregulation …

Antibodies to complement factor H are an uncommon cause of hemolytic uremic syndrome
(HUS). Information on clinical features and outcomes in children is limited. In order to …

The C3 amplification loop lies at the core of all the complement pathways, rather than the
alternative pathway alone. It is, in evolutionary terms, the oldest part of the complement …

Hemolytic uremic syndrome (HUS) is a rare disease. In this work the authors review the
recent findings on HUS, considering the different etiologic and pathogenetic classifications …

Atypical hemolytic uremic syndrome (aHUS) is a heterogeneous disease that is caused by
defective complement regulation in over 50% of cases. Mutations have been identified in …

Atypical hemolytic uremic syndrome (aHUS) is a rare syndrome of hemolysis,
thrombocytopenia, and renal insufficiency. Genetic mutations in the alternate pathway of …