Placental contribution to nutritional programming of health and diseases: epigenetics and sexual dimorphism

A Tarrade, P Panchenko, C Junien… - Journal of …, 2015 - journals.biologists.com
The recent and rapid worldwide increase in non-communicable diseases challenges the
assumption that genetic factors are the primary contributors to such diseases. A new concept …

Gestational hypoxia and developmental plasticity

CA Ducsay, R Goyal, WJ Pearce… - Physiological …, 2018 - journals.physiology.org
Hypoxia is one of the most common and severe challenges to the maintenance of
homeostasis. Oxygen sensing is a property of all tissues, and the response to hypoxia is …

[HTML][HTML] Placental pathology, perinatal death, neonatal outcome, and neurological development: a systematic review

AM Roescher, A Timmer, JJHM Erwich, AF Bos - PloS one, 2014 - journals.plos.org
Background The placenta plays a crucial role during pregnancy for growth and development
of the fetus. Less than optimal placental performance may result in morbidity or even …

DNA methylation alterations in response to prenatal exposure of maternal cigarette smoking: a persistent epigenetic impact on health from maternal lifestyle?

CH Nielsen, A Larsen, AL Nielsen - Archives of toxicology, 2016 - Springer
Despite increased awareness, maternal cigarette smoking during pregnancy continues to be
a common habit causing risk for numerous documented negative health consequences in …

Identifying placental epigenetic alterations in an intrauterine growth restriction (IUGR) rat model induced by gestational protein deficiency

SM Reamon-Buettner, J Buschmann, G Lewin - Reproductive Toxicology, 2014 - Elsevier
Poor maternal nutrition during gestation can lead to intrauterine growth retardation (IUGR), a
main cause of low birth weight associated with high neonatal morbidity and mortality. Such …

[HTML][HTML] Long non-coding RNAs in placental development and disease

T Basak, R Ain - Non-coding RNA Investigation, 2019 - ncri.amegroups.org
To reconceptualize epitranscriptomics, long non-coding RNAs (lncRNAs) are emerging as
future frontiers in the paradigm shift of stereotyped biological science. Long non-coding …

Clustering and classical analysis of clinical and placental phenotypes in fetal growth restriction and constitutional fetal smallness

J Stanek, J Biesiada - Placenta, 2016 - Elsevier
This study aims to determine whether placental examination can be used to distinguish
between pathologic fetal growth restriction (FGR) and constitutional fetal smallness. Data …

DNA methylation and expression patterns of selected genes in first-trimester placental tissue from pregnancies with small-for-gestational-age infants at birth

M Leeuwerke, MS Eilander, MGM Pruis… - Biology of …, 2016 - academic.oup.com
Variations in DNA methylation levels in the placenta are thought to influence gene
expression and are associated with complications of pregnancy, like fetal growth restriction …

Aberrant hydroxymethylation of ANGPTL4 is associated with selective intrauterine growth restriction in monochorionic twin pregnancies

Y Zhang, D Zheng, Q Fang, M Zhong - Epigenetics, 2020 - Taylor & Francis
Selective intrauterine growth restriction (sIUGR) is a severe complication in monochorionic
(MC) twin pregnancies, and it carries increased risks of poor prognosis. Current data …

[HTML][HTML] The promoter methylomes of monochorionic twin placentas reveal intrauterine growth restriction-specific variations in the methylation patterns

Z He, H Lu, H Luo, F Gao, T Wang, Y Gao, Q Fang… - Scientific Reports, 2016 - nature.com
Intrauterine growth restriction (IUGR) affects the foetus and has a number of pathological
consequences throughout life. Recent work has indicated that variations in DNA methylation …