The first mammalian cellular DNA polymerase was discovered in 1958 [1]*, but it was not
until 1970 that the existence of multiple DNA polymerase activities was recognized in these …

We have studied the effect of glutathione reduction by buthionine sulf-oximine (BSO), a
specific inhibitor ofλ-glutamyl cysteine synthetase, on DNA repair after cisplatin damage in …

Under appropriate conditions, divalent copper, lead, and cadmium ions significantly inhibit
human DNA polymerase β (following accepted convention, the term DNA polymerase β …

This chapter focuses on cellular deoxyribonucleic acid (DNA) polymerases of higher
eukaryotes and only occasional note is made on enzymes of lower eukaryotes. It explores …

Abstract Simian virus 40 (SV40) nucleoprotein complexes were extracted from nuclei of
infected monkey cells and fractionated on neutral sucrose density gradients. Complexes …

Abstract An Adenovirus (Ad) DNA replication complex extracted from infected HeLa nuclei
could be purified free of the bulk of intracellular DNA polymerase activity by sedimention in …

The optimal condition for the rat DNA polymerase β activity with (rA) n·(dT) 12–18 as a
template· primer was determined. The activity was remarkably affected by the concentration …

Purified DNA polymerase β of calf thymus can utilize poly (rA) oligo (dT) as efficiently as poly
(dA). oligo (dT) or activated DNA as a template-primer. The poly (rA) dependent activity of …

The presence of 0.75 μM N-ethylmaleimide (NEM) during irradiation of synchronous HeLa
cells at different stages of their cycle enhances cell killing (ie, sensitizes) in early G1 and late …

A novel DNA polymerase, which could use both poly (rA)· oligo (dT) and activated calf
thymus DNA efficiently as template-primers, was purified 20 000-fold from calf thymus …