Puberty is a major maturational event; its mechanisms and timing are driven by genetic
determinants, but also controlled by endogenous and environmental cues. Substantial …

The tremendous increase in childhood obesity prevalence over the last few decades cannot
merely be explained by genetics and evolutionary changes in the genome, implying that …

STUDY QUESTION Do the epigenome-wide DNA methylation profiles of adolescents born
from ART differ from the epigenome of naturally conceived counterparts? SUMMARY …

During the last decades several lines of evidence reported the association of an adverse
intrauterine environment, leading to intrauterine restriction, with future disease, such as …

Background There is an increasing interest in the role of epigenetics in epidemiology, but
the emerging research field faces several critical biological and technical challenges. In …

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition, the underlying
pathological mechanisms of which are not yet completely understood. Although several …

DNA methylation (DNAm) is a dynamic, age-dependent epigenetic modification that can be
used to study interactions between genetic and environmental factors. Environmental …

Epigenetic factors have been suggested as mediators of early-life nutrition to future health.
Prior studies focused on breastfeeding effects on DNA methylation (DNAm), ignoring other …

Context Circulating concentrations of free triiodothyronine (fT3), free thyroxine (fT4), and
thyrotropin (TSH) are partly heritable traits. Recent studies have advanced knowledge of …

Graves disease and Hashimoto disease form part of the spectrum of autoimmune thyroid
disease (AITD), to which genetic and environmental factors are recognized contributors …