[HTML][HTML] Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia

K Leavey, SL Wilson, SA Bainbridge, WP Robinson… - Clinical …, 2018 - Springer
Background Preeclampsia (PE) is a heterogeneous, hypertensive disorder of pregnancy,
with no robust biomarkers or effective treatments. We hypothesized that this heterogeneity is …

[HTML][HTML] Mechanisms and functions of chemerin in cancer: potential roles in therapeutic intervention

WJ Shin, BA Zabel, RK Pachynski - Frontiers in immunology, 2018 - frontiersin.org
Chemerin [RARRES2 [retinoic acid receptor responder 2], TIG2 [tazarotene induced gene 2
(TIG2)]] is a multifunctional cytokine initially described in skin cultures upon exposure to the …

[HTML][HTML] Future directions in the diagnosis and medical treatment of adrenocortical carcinoma

SG Creemers, LJ Hofland… - Endocrine-related …, 2016 - erc.bioscientifica.com
Adrenocortical carcinoma (ACC) is a rare disease with a poor prognosis. Discrimination
between ACCs and adrenocortical adenomas (ACAs) remains challenging, with the current …

[HTML][HTML] Genetics of tumors of the adrenal cortex

F Bonnet-Serrano, J Bertherat - Endocrine-related cancer, 2018 - erc.bioscientifica.com
This review describes the molecular alterations observed in the various types of tumors of
the adrenal cortex, excluding Conn adenomas, especially the alterations identified by …

Characterization of DNA methylation-based markers for human body fluid identification in forensics: a critical review

F Kader, M Ghai, AO Olaniran - International journal of legal medicine, 2020 - Springer
Body fluid identification in crime scene investigations aids in reconstruction of crime scenes.
Several studies have identified and reported differentially methylated sites (DMSs) and …

Functional epigenetic approach identifies frequently methylated genes in Ewing sarcoma

A Alholle, AT Brini, S Gharanei, S Vaiyapuri… - Epigenetics, 2013 - Taylor & Francis
Using a candidate gene approach we recently identified frequent methylation of the RASSF2
gene associated with poor overall survival in Ewing sarcoma (ES). To identify effective …

Management of endocrine disease: adrenocortical carcinoma: differentiating the good from the poor prognosis tumors

A Jouinot, J Bertherat - European Journal of Endocrinology, 2018 - academic.oup.com
Adrenocortical carcinoma (ACC) is a rare malignancy with a poor prognosis, the five-years
overall survival being below 40%. However, there is great variability of outcomes and we …

Diagnostic and prognostic role of steroidogenic factor 1 in adrenocortical carcinoma: a validation study focusing on clinical and pathologic correlates

E Duregon, M Volante, J Giorcelli, M Terzolo, E Lalli… - Human pathology, 2013 - Elsevier
The pathologic characterization of adrenocortical cancer is still problematic for several
reasons, including the identification of novel markers of diagnostic or prognostic relevance …

DNA methylation is an independent prognostic marker of survival in adrenocortical cancer

A Jouinot, G Assie, R Libe, M Fassnacht… - The Journal of …, 2017 - academic.oup.com
Context: Adrenocortical cancer (ACC) is an aggressive tumor with a heterogeneous
outcome. Prognostic stratification is difficult even based on tumor stage and Ki67. Recently …

[HTML][HTML] TOP2A is overexpressed in and a therapeutic target for adrenocortical carcinoma

M Jain, L Zhang, M He, YQ Zhang… - Endocrine-related …, 2013 - ncbi.nlm.nih.gov
Background Adrenocortical carcinoma (ACC) is a rare but aggressive malignancy with no
effective therapy for patients with locally advanced and metastatic disease. The current study …