Childhood trauma (CT) can have persistent effects on the brain and is one of the major risk
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …

Maternal mental health may be considered a determining factor influencing fetal and child
development. An essential factor with potentially negative consequences for a child's …

Short-chain fatty acids (SCFAs, especially butyric acid) have been demonstrated to play a
promising role in the development of autism spectrum disorders (ASD). Recently, the …

The impacts of glucocorticoids (GCs) are mainly mediated by a nuclear receptor (GR)
existing in almost every tissue. The GR regulates a wide range of physiological functions …

Diabetes is a complex and heterogeneous disorder characterized by chronic hyperglycemia.
Its core cause is progressively impaired insulin secretion by pancreatic β-cell failures …

Depression is a highly prevalent, disabling, and often chronic illness that places substantial
burdens on patients, families, healthcare systems, and the economy. A substantial minority …

The endocannabinoid system (ECS) regulates brain development and function, energy
metabolism and stress in a sex-, age-and tissue-dependent manner. The ECS comprises …

Recent studies imply that there is a tight association between epigenetics and a molecular
mechanism of major depressive disorder (MDD). Epigenetic modifications, ie, DNA …

Background: Major depression has a complex and multifactorial etiology constituted by the
interaction between genetic and environmental factors in its development. Objective: The …

Early adversity is an important risk factor that influences brain aging. Diverse animal models
of early adversity, including gestational stress and postnatal paradigms disrupting dam-pup …