Disulfiram protects against abdominal aortic aneurysm by ameliorating vascular smooth muscle cells pyroptosis

F Liao, L Wang, Z Wu, G Luo, Y Qian, X He… - … drugs and therapy, 2023 - Springer
Purpose Recent studies demonstrated that pyroptosis is involved in abdominal aortic
aneurysm (AAA) progression, suggesting a potential target for AAA treatment. This study …

Swiss Vascular Biobank: Evaluation of Optimal Extraction Method and Admission Solution for Preserving RNA from Human Vascular Tissue

J Pelisek, Y Yundung, B Reutersberg, L Meuli… - Journal of Clinical …, 2023 - mdpi.com
Proper biobanking is essential for obtaining reliable data, particularly for next-generation
sequencing approaches. Diseased vascular tissues, having extended atherosclerotic …

Biocompatible Magnetic Poly (carbonate urethane) Microspheres for Potential Applications in Aneurysm Embolization

W Wei, J Yang, Z Zhang, Y Dai, W Li… - ACS Applied Polymer …, 2022 - ACS Publications
Poor durability and lack of neointima formation of microcoils used in transcatheter arterial
embolization of aneurysms can increase the risk of recanalization, which may necessitate …

[HTML][HTML] Identification of biomarkers and analysis of infiltrated immune cells in stable and ruptured abdominal aortic aneurysms

Y Chen, T Ouyang, C Fang, C Tang, K Lei… - Frontiers in …, 2022 - frontiersin.org
Objectives: The mortality rate of abdominal aortic aneurysm (AAA) is extremely high in the
older population. This study aimed to identify potential biomarkers of AAA and aortic rupture …

The future for the therapeutics of abdominal aortic aneurysm: engineered nanoparticles drug delivery for abdominal aortic aneurysm

P Du, Y Hou, C Su, J Gao, Y Yang, J Zhang… - … in Bioengineering and …, 2024 - frontiersin.org
Abdominal aortic aneurysm (AAA) is a severe cardiovascular disease with a high mortality
rate. Several screening and diagnostic methods have been developed for AAA early …

[HTML][HTML] Vascular Biology of arterial aneurysms

D Costa, M Andreucci, N Ielapi, GF Serraino… - Annals of Vascular …, 2023 - Elsevier
Objective This review aims to analyze biomolecular and cellular events responsible for
arterial aneurysm formation with particular attention to vascular remodeling that determines …

Anaesthesia for vascular emergencies–a state of the art review

N Boucher, H Dreksler, J Hooper, S Nagpal… - …, 2023 - Wiley Online Library
In this state‐of‐the‐art review, we discuss the presenting symptoms and management
strategies for vascular emergencies. Although vascular emergencies are best treated at a …

Instabilities of an inflated and extended doubly fiber-reinforced cylindrical membrane under damage processes and different natural configurations of its constituents …

H Topol, H Nazari, M Stoffel, B Markert, J Lacalle… - Thin-Walled …, 2024 - Elsevier
This article studies extended and inflated tubes made of doubly fiber-reinforced hyperelastic
material in which the constituents undergo damage processes at large deformations …

PINK1 dominated mitochondria associated genes signature predicts abdominal aortic aneurysm with metabolic syndrome

K Wang, Z Zhou, L Huang, Q Kan, Z Wang… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Abdominal aortic aneurysm (AAA) is typically asymptomatic but a devastating cardiovascular
disorder, with overall mortality exceeding 80% once it ruptures. Some patients with AAA may …

[HTML][HTML] Doxycycline induces mitochondrial dysfunction in aortic smooth muscle cells

C Yap, S Wanga, RCI Wüst, BW van Os, MME Pijls… - Vascular …, 2024 - Elsevier
The antibiotic doxycycline is known to inhibit inflammation and was therefore considered as
a therapeutic to prevent abdominal aortic aneurysm (AAA) growth. Yet mitochondrial …