[HTML][HTML] Recent advances in our understanding of recurrent primary glomerulonephritis after kidney transplantation

FG Cosio, DC Cattran - Kidney international, 2017 - Elsevier
Recurrent glomerulonephritis (GN) is an important cause of kidney allograft failure,
particularly in younger recipients. Approximately 15% of death-censored graft failures are …

Treatment of B-cell disorder improves renal outcome of patients with monoclonal gammopathy–associated C3 glomerulopathy

S Chauvet, V Frémeaux-Bacchi… - Blood, The Journal …, 2017 - ashpublications.org
The high frequency of monoclonal gammopathy in adult patients with C3 glomerulopathy
(C3G) emphasizes the role of monoclonal immunoglobulin (MIg) in the occurrence of renal …

[HTML][HTML] Atypical postinfectious glomerulonephritis is associated with abnormalities in the alternative pathway of complement

S Sethi, FC Fervenza, Y Zhang, L Zand, NC Meyer… - Kidney international, 2013 - Elsevier
Postinfectious glomerulonephritis is a common disorder that develops following an infection.
In the majority of cases, there is complete recovery of renal function within a few days to …

[HTML][HTML] Membranoproliferative glomerulonephritis and C3 glomerulopathy: resolving the confusion

S Sethi, CM Nester, RJH Smith - Kidney international, 2012 - Elsevier
Membranoproliferative glomerulonephritis (MPGN) denotes a general pattern of glomerular
injury that is easily recognized by light microscopy. With additional studies, MPGN …

Diseases of complement dysregulation—an overview

EKS Wong, D Kavanagh - Seminars in immunopathology, 2018 - Springer
Atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy (C3G), and paroxysmal
nocturnal hemoglobinuria (PNH) are prototypical disorders of complement dysregulation …

Clinical findings, pathology, and outcomes of C3GN after kidney transplantation

L Zand, EC Lorenz, FG Cosio… - Journal of the …, 2014 - journals.lww.com
Abstract C3 glomerulonephritis (C3GN) results from abnormalities in the alternative pathway
of complement, and it is characterized by deposition of C3 with absent or scant Ig deposition …

C3 glomerulopathy: ten years' experience at Mayo Clinic

A Ravindran, FC Fervenza, RJH Smith… - Mayo Clinic …, 2018 - Elsevier
Objective To describe the clinicopathological features, complement abnormalities, triggers,
treatment, and outcomes of C3 glomerulopathy. Patients and Methods A total of 114 patients …

C3 glomerulonephritis associated with monoclonal gammopathy: a case series

L Zand, A Kattah, FC Fervenza, RJH Smith… - American journal of …, 2013 - Elsevier
Background C3 glomerulonephritis (GN) is a proliferative GN resulting from glomerular
deposition of complement factors due to dysregulation of the alternative pathway of …

[HTML][HTML] C3 glomerulopathy associated with monoclonal Ig is a distinct subtype

A Ravindran, FC Fervenza, RJH Smith, S Sethi - Kidney international, 2018 - Elsevier
Monoclonal immunoglobulins (MIg) may play a causal role in C3 glomerulopathy (C3G) by
impairing regulation of the alternative pathway of complement. Ninety-five patients with C3G …

Pathogenesis of the C3 glomerulopathies and reclassification of MPGN

AS Bomback, GB Appel - Nature Reviews Nephrology, 2012 - nature.com
Until recently, membranoproliferative glomerulonephritis (MPGN) was clinically classified as
either primary, idiopathic MPGN or as secondary MPGN when an underlying aetiology was …