Antioxidant, anti-obesity, nutritional and other beneficial effects of different chili pepper: A review
Fruits and vegetables are important components of a healthy diet. They are rich sources of
vitamins and minerals, dietary fibre and a host of beneficial non-nutrient substances …
vitamins and minerals, dietary fibre and a host of beneficial non-nutrient substances …
Structural mechanisms of transient receptor potential ion channels
E Cao - Journal of General Physiology, 2020 - rupress.org
Transient receptor potential (TRP) ion channels are evolutionarily ancient sensory proteins
that detect and integrate a wide range of physical and chemical stimuli. TRP channels are …
that detect and integrate a wide range of physical and chemical stimuli. TRP channels are …
Biomedical and antioxidant potentialities in chilli: Perspectives and way forward
Worldwide, since ages and nowadays, traditional medicine is well known, owing to its
biodiversity, which immensely contributed to the advancement and development of …
biodiversity, which immensely contributed to the advancement and development of …
Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands
N Su, W Zhen, H Zhang, L Xu, Y Jin, X Chen… - Nature Chemical …, 2023 - nature.com
The transient receptor potential vanilloid 2 (TRPV2) ion channel is a polymodal receptor
widely involved in many physiological and pathological processes. Despite many TRPV2 …
widely involved in many physiological and pathological processes. Despite many TRPV2 …
Simulation and machine learning methods for ion-channel structure determination, mechanistic studies and drug design
Ion channels are expressed in almost all living cells, controlling the in-and-out
communications, making them ideal drug targets, especially for central nervous system …
communications, making them ideal drug targets, especially for central nervous system …
Structural basis for promiscuous action of monoterpenes on TRP channels
Monoterpenes are major constituents of plant-derived essential oils and have long been
widely used for therapeutic and cosmetic applications. The monoterpenes menthol and …
widely used for therapeutic and cosmetic applications. The monoterpenes menthol and …
Insights from molecular dynamics simulations of TRPV1 channel modulators in pain
TRPV1 is a nonselective cation channel vital for detecting noxious stimuli (heat, acid,
capsaicin). Its role in pain makes it a potential drug target for chronic pain management …
capsaicin). Its role in pain makes it a potential drug target for chronic pain management …
Structural and evolutionary insights point to allosteric regulation of TRP ion channels
Conspectus The familiar pungent taste of spicy food, the refreshing taste of mint, and many
other physiological phenomena are mediated by transient receptor potential (TRP) ion …
other physiological phenomena are mediated by transient receptor potential (TRP) ion …
Evidence that the TRPV1 S1-S4 membrane domain contributes to thermosensing
Sensing and responding to temperature is crucial in biology. The TRPV1 ion channel is a
well-studied heat-sensing receptor that is also activated by vanilloid compounds, including …
well-studied heat-sensing receptor that is also activated by vanilloid compounds, including …
Molecular determinants for the chemical activation of the warmth-sensitive TRPV3 channel by the natural monoterpenoid carvacrol
C Niu, X Sun, F Hu, X Tang, KW Wang - Journal of Biological Chemistry, 2022 - ASBMB
Transient receptor potential vanilloid 3 (TRPV3), robustly expressed in the skin, is a
nonselective calcium-permeable cation channel activated by warm temperature, voltage …
nonselective calcium-permeable cation channel activated by warm temperature, voltage …