Background Changes in DNA methylation in the mammalian genome during development
are frequent events and play major roles regulating gene expression and other …

The mitochondrial ATP synthase is a multi-subunit enzyme complex located in the inner
mitochondrial membrane which is essential for oxidative phosphorylation under …

Identification of body fluids found at crime scenes provides important information that can
support a link between sample donors and actual criminal acts. Previous studies have …

Tissue specific differentially methylated regions (TDMRs) were identified and localized in the
mouse genome using second generation virtual RLGS (vRLGS). Sequenom MassARRAY …

Body fluid identification in crime scene investigations aids in reconstruction of crime scenes.
Several studies have identified and reported differentially methylated sites (DMSs) and …

Although most CpG islands are generally thought to remain unmethylated in all adult
somatic tissues, recent genome-wide approaches have found that some CpG islands have …

DNA methylation undergoes dynamic changes during development and cell differentiation.
Recent genome-wide studies discovered that tissue-specific differentially methylated …

Hepatocellular carcinoma (HCC) is known to be associated with both HBV and HCV. While
epigenetic changes have been previously reported to be associated with hepatocellular …

The cellular level of TDP-43 (also known as TARDBP) is tightly regulated; increases or
decreases in TDP-43 have deleterious effects in cells. The predominant mechanism …

Recent discoveries indicate a genetic basis for high-altitude adaptation among human
groups who have resided at high altitude for millennia, including Andeans, Tibetans, and …