Objectives To investigate the association between the MTHFR 677C→ T polymorphism and
coronary heart disease, assessing small study bias and heterogeneity between studies …

Open spina bifida remains a major source of disability despite an overall decrease in
incidence. It is frequently diagnosed prenatally and can thus–potentially–be treated by fetal …

Association of two key variants mapping to the MTHFR gene (C677T (rs1801133) and
A1298C (rs1801131)) with response to methotrexate (MTX) remains controversial. We …

This study concerns life satisfaction and its determinants in Dutch young adults with spina
bifida (SB). Data on life satisfaction (Life Satisfaction Questionnaire [LiSat‐9]) were related to …

Objective To assess the role of magnetic resonance imaging (MRI) in the prenatal diagnosis
of neural tube defects (NTDs). Background NTDs comprise a heterogeneous group of …

Folate has received international attention regarding its role in the risk-reduction of birth
defects, specifically neural tube defects (NTDs). In 1998, health officials in Canada, like the …

The International Clearinghouse for Birth Defects, Surveillance and Research reports a rise
in the prevalence rate of spina bifida in Japan. We determined first-trimester folate status of …

Object The authors present a novel cine magnetic resonance (MR) imaging, two-
dimensional (2D) fast imaging employing steady-state acquisition (FIESTA) technique with …

Object Postnatal improvement in Chiari malformation type II (CM-II) following surgical repair
of myelomeningocele was evaluated. Methods The authors reviewed data obtained in 20 …

This article presents a general overview of fetal sonography and an approach to the
sonographic evaluation of the fetal central nervous system. Annotated images of anomalies …