Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …

Cervical cancer screening will rely, increasingly, on HPV testing as a primary screen. The
requirement for triage tests which can delineate clinically significant infection is thus …

Background To conduct a meta-analysis of performance of DNA methylation in women with
high-grade cervical intraepithelial neoplasia (CIN2+). Methods Medline and Embase …

This paper briefly reviews the role of hypermethylation of host cell genes in cervical
carcinogenesis and discusses potential clinical applications of methylation analysis in the …

Background: Human papillomavirus (HPV) testing provides a much more sensitive method
of detection for high-grade lesions than cytology, but specificity is low. Here, we explore the …

Epigenetics is the study of heritable and non-heritable genetic coding that is additive to
information contained within classical DNA base pair sequences. Differential methylation …

This review gives an overview of current screening practices for cervical cancer. In the
introduction, we will cover approaches of population screening focusing on high-risk Human …

Abstract Purpose: Human papillomavirus (HPV) DNA methylation testing is a promising
triage option for women testing HPV positive during cervical cancer screening. However, the …

Cervical cancer is the most prevalent gynecologic malignancy, especially in women of low-
and middle-income countries (LMICs). With a better understanding of the etiology and …

Human papillomavirus (HPV)‐based cervical cancer screening requires triage of HPV
positive women to identify those at risk of cervical intraepithelial neoplasia grade 2 (CIN2) or …