Epigenetic regulation in cardiovascular disease: mechanisms and advances in clinical trials
Y Shi, H Zhang, S Huang, L Yin, F Wang… - … and Targeted Therapy, 2022 - nature.com
Epigenetics is closely related to cardiovascular diseases. Genome-wide linkage and
association analyses and candidate gene approaches illustrate the multigenic complexity of …
association analyses and candidate gene approaches illustrate the multigenic complexity of …
Modern epigenetics methods in biological research
Y Li - Methods, 2021 - Elsevier
The definition of epigenetics refers that molecular modifications on DNA that can regulate
gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics …
gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics …
Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases
M Chin-Chan, J Navarro-Yepes… - Frontiers in cellular …, 2015 - frontiersin.org
Neurodegenerative diseases including Alzheimer (AD) and Parkinson (PD) have attracted
attention in last decades due to their high incidence worldwide. The etiology of these …
attention in last decades due to their high incidence worldwide. The etiology of these …
What do you mean,“epigenetic”?
C Deans, KA Maggert - Genetics, 2015 - academic.oup.com
Interest in the field of epigenetics has increased rapidly over the last decade, with the term
becoming more identifiable in biomedical research, scientific fields outside of the molecular …
becoming more identifiable in biomedical research, scientific fields outside of the molecular …
The bacterial epigenome
MA Sánchez-Romero, J Casadesús - Nature Reviews Microbiology, 2020 - nature.com
In all domains of life, genomes contain epigenetic information superimposed over the
nucleotide sequence. Epigenetic signals control DNA–protein interactions and can cause …
nucleotide sequence. Epigenetic signals control DNA–protein interactions and can cause …
Genomics of local adaptation with gene flow
A Tigano, VL Friesen - Molecular ecology, 2016 - Wiley Online Library
Gene flow is a fundamental evolutionary force in adaptation that is especially important to
understand as humans are rapidly changing both the natural environment and natural levels …
understand as humans are rapidly changing both the natural environment and natural levels …
[HTML][HTML] Role of epigenetics in biology and human diseases
A Moosavi, AM Ardekani - Iranian biomedical journal, 2016 - ncbi.nlm.nih.gov
For a long time, scientists have tried to describe disorders just by genetic or environmental
factors. However, the role of epigenetics in human diseases has been considered from a …
factors. However, the role of epigenetics in human diseases has been considered from a …
Adult cell plasticity in vivo: de-differentiation and transdifferentiation are back in style
AJ Merrell, BZ Stanger - Nature reviews Molecular cell biology, 2016 - nature.com
Biologists have long been intrigued by the possibility that cells can change their identity, a
phenomenon known as cellular plasticity. The discovery that terminally differentiated cells …
phenomenon known as cellular plasticity. The discovery that terminally differentiated cells …
Epigenetics of stress-related psychiatric disorders and gene× environment interactions
A deeper understanding of the pathomechanisms leading to stress-related psychiatric
disorders is important for the development of more efficient preventive and therapeutic …
disorders is important for the development of more efficient preventive and therapeutic …
Epigenetic modifications: basic mechanisms and role in cardiovascular disease
DE Handy, R Castro, J Loscalzo - Circulation, 2011 - Am Heart Assoc
The term epigenetics was first used to refer to the complex interactions between the genome
and the environment that are involved in development and differentiation in higher …
and the environment that are involved in development and differentiation in higher …