Phylogenetic analysis of 11 genetic loci and results from many genotyping studies revealed
significant genetic diversity with the pathogenic Cryptococcus gattii/Cryptococcus …

During the latter half of the twentieth century, fungal pathogens such as Cryptococcus
neoformans were increasingly recognized as a significant threat to the health of immune …

Cryptococcosis is mainly caused by Cryptococcus neoformans. However, the number of
cases due to C. gattii is increasing, affecting mainly immunocompetent hosts. C. gattii is …

The interactions between a host and microbe drive the health and disease status of the host.
Of importance is the cause of dysbiosis in the presence of a pathogen, and critically, the …

Most cases of cryptococcosis are caused by Cryptococcus neoformans var. grubii (serotype
A), which is widespread in the environment, where it is primarily associated with pigeon …

Animal models of fungal infections are, and will remain, a key tool in the advancement of the
medical mycology. Many different types of animal models of fungal infection have been …

The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …

Cryptococcus neoformans is a leading cause of fungal brain infection, but the mechanism of
dissemination and dynamics of cerebral infection following pulmonary disease are poorly …

Fungal pathogens cause an array of diseases by targeting both immunocompromised and
immunocompetent hosts. Fungi overcome our current arsenal of antifungals through the …

The in vivo antifungal activity of the naphthoquinone beta-lapachone against disseminated
infection by Cryptococcus neoformans was investigated. Swiss mice were …