Loss of function TET2 mutation (TET2 MT) is one of the most frequently observed lesions in
clonal haematopoiesis (CH). TET2 a member TET-dioxygenase family of enzyme that along …

Abstract O-linked-N-acetylglucosaminylation (O-GlcNAcylation), a dynamic post-
translational modification (PTM), holds profound implications in controlling various cellular …

Bivalent chromatin is defined by the co-occurrence of otherwise opposing H3K4me3 and
H3K27me3 modifications and is typically located at unmethylated promoters of lowly …

Exposure to arsenic during gestation has lasting health-related effects on the developing
fetus, including an increase in the risk of metabolic disease later in life. Epigenetics is a …

Regulation of cell fate requires the establishment and erasure of 5-methylcytosine (5mC) in
genomic DNA. The formation of 5mC is achieved by DNA cytosine methyltransferases …

Despite extensive research over the last few decades, the etiology of schizophrenia (SZ)
remains unclear. SZ is a pathological disorder that is highly debilitating and deeply affects …

Although the COVID-19 pandemic appears to be diminishing, the emergence of SARS-CoV-
2 variants represents a threat to humans due to their inherent transmissibility, immunological …

Background Currently, the prevalence of Alzheimer's disease (AD) is progressively rising,
particularly in developed nations. There is an escalating focus on the onset and progression …

Wnt/β-catenin signaling is a critical pathway that influences development and therapeutic
response of non-small cell lung cancer (NSCLC). In recent years, many Wnt regulators …

Elevated plasma total homocysteine (tHcy) is associated with the development of
Alzheimer's disease and other forms of dementia. In this study, we report the relationship …