In macropinocytosis, cells take up micrometre-sized droplets of medium into internal
vesicles. These vesicles are acidified and fused to lysosomes, their contents digested and …

Macropinocytosis is an important mechanism of internalizing extracellular materials and
dissolved molecules in eukaryotic cells. Macropinocytosis has a dual effect on cancer cells …

Opportunistic infections by environmental fungi are a growing clinical problem, driven by an
increasing population of people with immunocompromising conditions. Spores of the …

Cryptococcus neoformans is a facultative intracellular pathogen and its interaction with
macrophages is a key event determining the outcome of infection. Urease is a major …

The observation that some aspects of amoeba-fungal interactions resemble animal
phagocytic cell-fungal interactions, together with the finding that amoeba passage can …

Microbes gain access to eukaryotic cells as food for bacteria-grazing protists, for host
protection by microbe-killing immune cells, or for microbial benefit when pathogens enter …

Cryptococcus species are environmental fungal pathogens and the causative agents of
cryptococcosis. Infection occurs upon inhalation of infectious particles, which proliferate in …

Acanthamoeba is known to interact with a plethora of microorganisms such as bacteria,
fungi and viruses. In these interactions, the amoebae can be predatory in nature …

Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

Amoeboid predators, such as amoebae, are proposed to select for survival traits in soil
microbes such as Cryptococcus neoformans; these traits can also function in animal …