Highlights•Epigenetic code plays an important role in insect brain plasticity.•Epialleles may
be essential in driving behavioural adaptation in insects.•Insect research needs to move …

A dysregulated hypothalamic-pituitary-adrenal (HPA) axis has repeatedly been
demonstrated to play a fundamental role in psychiatric disorders and suicide, yet the …

General anesthetics given to immature rodents cause delayed neurobehavioral
abnormalities via incompletely understood mechanisms. DNA methylation, one of the …

An emerging paradigm shift for disease diagnosis is to rely on molecular characterization
beyond traditional clinical and symptom-based examinations. Although genetic alterations …

Background The brain is a common target of metastases for melanoma patients. Little is
known about the genetic and epigenetic alterations in melanoma brain metastases (MBMs) …

Manganese (Mn) is an essential cofactor for many enzymes and plays an important role in
normal growth and development. However, excess exposure to manganese (Mn) may be an …

Hippocampal memory formation is highly regulated by post-translational histone
modifications and DNA methylation. Accordingly, these epigenetic processes play a major …

Post-traumatic stress disorder (PTSD) is a psychiatric condition characterized by intrusive
and persistent memories of a psychologically traumatic event that leads to significant …

The recent years have witnessed an exponential growth in the knowledge of epigenetic
mechanisms, and piling evidence now links DNA methylation and histone modifications with …

Epigenetic mechanisms such as DNA methylation (DNAm) have been associated with stress
responses and increased vulnerability to depression. Abnormal DNAm is observed in …