Stress and antidepressant treatment can modulate DNA methylation in promoter region of
genes related to neuroplasticity and mood regulation, thus implicating this epigenetic …

Huntington's disease (HD) can be considered the paradigm of epigenetic dysregulation in
neurodegenerative disorders. In this review, we attempted to compile the evidence that …

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by
impaired social interactions, language deficits, as well as restrictive or repetitive behaviors …

Schizophrenia (SZ) is a heritable, nonmendelian, neurodevelopmental disorder in which
epigenetic dysregulation of the brain genome plays a fundamental role in mediating the …

Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric diseases that are
characterized by abnormalities of thought, behaviour, cognition and mood. The genetic …

Despite extensive research over the last few decades, the etiology of schizophrenia (SZ)
remains unclear. SZ is a pathological disorder that is highly debilitating and deeply affects …

Although epigenetic abnormalities have been described in Huntington's disease (HD), the
causal epigenetic mechanisms driving neurodegeneration in HD cortex and striatum remain …

Less than 1.5% of the human genome encodes protein. However, vast portions of the
human genome are subject to transcriptional and epigenetic regulation, and many …

Teenage binge drinking is a major health concern in the United States, with 21% of
teenagers reporting binge-pattern drinking behavior in the previous 30 days. Recently, our …

Mounting evidence has recently underscored the importance of DNA methylation in normal
brain functions. DNA methylation machineries are responsible for dynamic regulation of …