Recently, long noncoding RNAs (lncRNAs) have attracted great attention from researchers.
LncRNAs are non-protein-coding RNAs of more than 200 nucleotides in length. Multiple …

The pig was first used in biomedical research in ancient Greece and over the past few
decades has quickly grown into an important biomedical research tool. Pigs have genetic …

Glioblastoma multiforme (GBM) is the most common and aggressive adult primary brain
cancer, with< 10% of patients surviving for more than 3 years. Demographic and clinical …

Even with a rare occurrence of only 1.35% of cancer cases in the United States of America,
brain tumors are considered as one of the most lethal malignancies. The most aggressive …

Although massive amounts of condition-specific molecular profiles are being accumulated in
public repositories every day, meaningful interpretation of these data remains a major …

Causal mediation modeling has become a popular approach for studying the effect of an
exposure on an outcome through mediators. Currently, the literature on mediation analyses …

The brain is an ever‐changing organ that encodes memories and directs behavior.
Neuroanatomical studies have revealed structural plasticity of neural architecture, and …

Background & Objective: Gliomas constitute 81% of malignant brain tumors and exhibit a
poor prognosis. Two main events involved in the progression of gliomas are the …

Effective and powerful survival mediation models are currently lacking. To partly fill such
knowledge gap, we particularly focus on the mediation analysis that includes multiple DNA …

Emotion dysregulation has been implicated as a risk factor for many psychiatric conditions.
Therefore, examining genetic risk associated with emotion dysregulation could help inform …