Background Cryptococcosis and talaromycosis are known as 'neglected epidemics' due to
their high case fatality rates and low concern. Clinically, the skin lesions of the two fungal …

Plants have been reported as used by local populations to treat various infections for a long
time, which has directed several pharmacological studies. The main aim of this work was to …

Fungal pathogens of the Cryptococcus neoformans species complex (C. neoformans SC)
are a major cause of fungal meningitis in immunocompromised individuals. As with other …

Cryptococcosis is a potentially lethal fungal infection of humans caused by organisms within
the Cryptococcus neoformans/gattii species complex. Whilst C. neoformans is a relatively …

Introduction Fungal infections are increasingly encountered in clinical practice due to more
favorable environmental conditions and increasing prevalence of immunocompromised …

Genetic diversity analyses were performed by sero-genotyping and multi-locus sequence
typing on 252 cryptococcal isolates from 13 HIV-positive Ivorian patients followed-up for …

C-type lectin receptors (CLRs) are diverse, trans-membrane proteins that function as pattern
recognition receptors (PRRs) which are necessary for orchestrating immune responses …

Caspase recruitment domain-containing protein 9 (CARD9) is a critical adaptor molecule
triggered by the interaction of C-type lectin receptors (CLRs) with carbohydrate motifs found …

Cryptococcus neoformans is a ubiquitous, opportunistic fungal pathogen that kills over
600,000 people annually. Here, we report integrated computational and experimental …

The mature phagosome of macrophages is a hostile environment for the vast majority of
phagocytosed microbes. In addition to active destruction of the engulfed microbes by …