The complement system was discovered at the end of the 19th century as a heat-labile
plasma component that “complemented” the antibodies in killing microbes, hence the name …

Atypical hemolytic uremic syndrome (aHUS) is a rare disorder characterized by
dysregulation of the alternate pathway. The diagnosis of aHUS is one of exclusion, which …

The complement system comprises the frontline of the innate immune system. Triggered by
pathogenic surface patterns in different pathways, the cascade concludes with the formation …

Thrombotic microangiopathy is a rare but serious complication that affects kidney transplant
recipients. It appears in 0.8–14% of transplanted patients and negatively affects graft and …

Abstract The World Health Organization estimates that approximately a quarter of the world's
population suffers from anemia, including almost half of preschool-age children. Globally …

Background and objectives Observing biomarkers that affect alternative pathway
dysregulation components may be effective in obtaining a new and more rapid diagnostic …

Atypical hemolytic uremic syndrome (aHUS) is a life-threatening disease causing systemic
thrombotic microangiopathy (TMA) due to the fact of complement dysregulation. Immune …

Dengue fever and chikungunya are viral diseases that have spread rapidly throughout the
world in recent decades. The occurrence of complications is well known, including prerenal …

Introduction: Atypical hemolytic uremic syndrome (aHUS) is a rare disorder characterized by
the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury …

Introduction Comprehensive information about atypical hemolytic uremic syndrome (aHUS)
is relatively scarce outside of Europe and North America. This narrative review assembles …