Aberrant methylation of the MGMT (O6-methylguanine-DNA methyltransferase) DNA-repair
gene is a predictive marker for the response to chemotherapy with alkylating agents (eg …

CpG island hypermethylation is a common occurrence in cancer. Because this is a stable
molecular alteration of the DNA, which can be detected easily from very small amounts, DNA …

Medulloblastoma (MB), the most devastating and common brain tumor in children, is highly
invasive and extremely difficult to treat. Identifying the properties of MB tumors that cause …

El papel crítico del remodelamiento de la cromatina en la expresión de los genes se halla
bajo la influencia de los cambios epigenéticos que conforman un lenguaje inesperado en el …

Chapter 8 addresses three different tumors: medulloblastoma, primitive neuroectodermal
tumors, and pineal tumors. The genetic and molecular studies in medulloblastoma are …

Melanoma research has made great advances in recent years. Particularly in the field of
immunology, melanoma researchers have opened new avenues for basic and translational …

Methylation‐specific PCR (MSP) of the mouse p53 gene has not yet been reported. We
searched the CpG islands, sequenced the bisulfited DNA, and designed PCR primers for …

Medulloblastoma (MB) is an embryonal brain tumor of the cerebellum. MB accounts for 4-6%
of all primary intracranial tumors. It is the most common malignant brain tumor in children it …

The therapy for medulloblastoma/primitive neuroectodermal tumors of the central nervous
system is surgery, followed by combination chemo-radiotherapy [1]. The radiation field is the …

Медуллобластома представляет собой гетерогенную группу опухолей с различными
морфологическими и клиническими вариантами. Изучение биологии медуллобластом …