Reestablishment of the endothelial lining by endothelial cell therapy stabilizes experimental abdominal aortic aneurysms

G Franck, J Dai, A Fifre, S Ngo, C Justine… - Circulation, 2013 - Am Heart Assoc
Background—Loss of the endothelium and its replacement by a thick thrombus are structural
features of human abdominal aortic aneurysms (AAAs). In AAAs, the relationship between …

Micro-RNAs in abdominal aortic aneurysms: insights from animal models and relevance to human disease

J Raffort, F Lareyre, M Clement… - Cardiovascular …, 2016 - academic.oup.com
Abdominal aortic aneurysm (AAA) is a major health concern and may be associated with
high rates of mortality linked to acute complications. Diagnosis and treatment are …

Pathophysiology of abdominal aortic aneurysm: Biomarkers and novel therapeutic targets

M Torres-Fonseca, M Galan, D Martinez-Lopez… - Clínica e Investigación …, 2019 - Elsevier
Abdominal aortic aneurysm (AAA) is a vascular pathology with a high rate of morbidity and
mortality and a prevalence that, in men over 65 years, can reach around 8%. In this disease …

Apolipoprotein E (ApoE) rescues the contractile smooth muscle cell phenotype in popliteal artery aneurysm disease

J Pauli, T Reisenauer, G Winski, N Sachs… - Biomolecules, 2023 - mdpi.com
Popliteal artery aneurysm (PAA) is the most frequent peripheral aneurysm, primarily seen in
male smokers with a prevalence below 1%. This exploratory study aims to shed light on …

Metformin inhibits abdominal aortic aneurysm formation through the activation of the AMPK/mTOR signaling pathway

J He, N Li, Y Fan, X Zhao, C Liu, X Hu - Journal of vascular research, 2021 - karger.com
Abstract Background and Objective: Epidemiological evidence suggests that the antidiabetic
drug metformin (MET) can also inhibit abdominal aortic aneurysm (AAA) formation …

[HTML][HTML] Low-dose aspirin and rupture of abdominal aortic aneurysm

H Wemmelund, TMM Jørgensen, A Høgh… - Journal of Vascular …, 2017 - Elsevier
Objective The use of low-dose aspirin (acetylsalicylic acid [ASA]) has been suggested to
attenuate growth of abdominal aortic aneurysms (AAAs), yet solid clinical evidence of this …

[图书][B] Vascular Biomechanics

TC Gasser - 2021 - Springer
The development of the vascular system was a critical step in the evolution of species. It
allowed organisms to meet the growing metabolic demands and opened the door for the …

Resveratrol counteracts systemic and local inflammation involved in early abdominal aortic aneurysm development

D Palmieri, B Pane, C Barisione, G Spinella… - Journal of Surgical …, 2011 - Elsevier
BACKGROUND: Monocyte activation, macrophage infiltration, vascular oxidative stress and
matrix proteolysis are inflammatory key steps contributing to abdominal aortic aneurysm …

Phylogenic determinants of cardiovascular frailty, focus on hemodynamics and arterial smooth muscle cells

JB Michel - Physiological reviews, 2020 - journals.physiology.org
The evolution of the circulatory system from invertebrates to mammals has involved the
passage from an open system to a closed in-parallel system via a closed in-series system …

The role of trace elements in cardiovascular diseases

C Wechselberger, B Messner, D Bernhard - Toxics, 2023 - mdpi.com
Essential trace elements play an important role in human physiology and are associated
with various functions regulating cellular metabolism. Non-essential trace elements, on the …