[HTML][HTML] Regeneration of hair cells from endogenous otic progenitors in the adult mammalian cochlea: Understanding its origins and future directions
N Smith-Cortinez, AK Tan, RJ Stokroos… - International Journal of …, 2023 - mdpi.com
Sensorineural hearing loss is caused by damage to sensory hair cells and/or spiral ganglion
neurons. In non-mammalian species, hair cell regeneration after damage is observed, even …
neurons. In non-mammalian species, hair cell regeneration after damage is observed, even …
[HTML][HTML] Research progress on the mechanism of cochlear hair cell regeneration
S Xu, N Yang - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Mammalian inner ear hair cells do not have the ability to spontaneously regenerate, so their
irreversible damage is the main cause of sensorineural hearing loss. The damage and loss …
irreversible damage is the main cause of sensorineural hearing loss. The damage and loss …
[HTML][HTML] DUSP5 regulated by YTHDF1-mediated m6A modification promotes epithelial-mesenchymal transition and EGFR-TKI resistance via the TGF-β/Smad …
W Fan, Y Xing, S Yan, W Liu, J Ning… - Cancer Cell …, 2024 - cancerci.biomedcentral.com
Lung adenocarcinoma (LUAD) patients have a dismal survival rate because of cancer
metastasis and drug resistance. The study aims to identify the genes that concurrently …
metastasis and drug resistance. The study aims to identify the genes that concurrently …
[HTML][HTML] Long-term survival of LGR5 expressing supporting cells after severe ototoxic trauma in the adult mouse cochlea
N Smith-Cortinez, FGJ Hendriksen… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
Methods Lgr5GFP transgenic mice and wild type mice aged postnatal day 30 (P30) and
P200 were used. P30 animals were deafened with a single dose of furosemide and …
P200 were used. P30 animals were deafened with a single dose of furosemide and …
Insights into the molecular mechanisms regulating mammalian hair cell regeneration
Z Hu, A Singh, II Dennis Bojrab… - Current Opinion in …, 2021 - journals.lww.com
Insights into the molecular mechanisms regulating mammalian... : Current Opinion in
Otolaryngology & Head and Neck Surgery Insights into the molecular mechanisms …
Otolaryngology & Head and Neck Surgery Insights into the molecular mechanisms …
[HTML][HTML] Hearing recovery induced by DNA demethylation in a chemically deafened adult mouse model
Functional hair cell regeneration in the adult mammalian inner ear remains challenging.
This study aimed to study the function of new hair cells induced by a DNA demethylating …
This study aimed to study the function of new hair cells induced by a DNA demethylating …
[HTML][HTML] Generation of a spiral ganglion neuron degeneration mouse model
Z Hu, F Komal, A Singh, M Deng - Frontiers in Cell and …, 2021 - frontiersin.org
Spiral ganglion neurons (SGNs) can be injured by a wide variety of insults. However, there
still is a lack of degeneration models to specifically damage the SGNs without disturbing …
still is a lack of degeneration models to specifically damage the SGNs without disturbing …
[图书][B] Determining the Role of Gata3 in a Sub-population of Vestibular Hair Cells
S Sheltz-Kempf - 2022 - search.proquest.com
The inner ear can be divided based on two functions: hearing and balance. The hearing
organ is called the cochlea, while the organs responsible for balance are collectively called …
organ is called the cochlea, while the organs responsible for balance are collectively called …