Regulation of neural circuit formation by protocadherins
SL Peek, KM Mah, JA Weiner - Cellular and molecular life sciences, 2017 - Springer
The protocadherins (Pcdhs), which make up the most diverse group within the cadherin
superfamily, were first discovered in the early 1990s. Data implicating the Pcdhs, including …
superfamily, were first discovered in the early 1990s. Data implicating the Pcdhs, including …
The molecular mechanisms of adaptive response related to environmental stress
A Rossnerova, A Izzotti, A Pulliero, A Bast… - International journal of …, 2020 - mdpi.com
The exposure of living organisms to environmental stress triggers defensive responses
resulting in the activation of protective processes. Whenever the exposure occurs at low …
resulting in the activation of protective processes. Whenever the exposure occurs at low …
Alcohol metabolism contributes to brain histone acetylation
Emerging evidence suggests that epigenetic regulation is dependent on metabolic state,
and implicates specific metabolic factors in neural functions that drive behaviour. In neurons …
and implicates specific metabolic factors in neural functions that drive behaviour. In neurons …
Estimation of a significance threshold for epigenome‐wide association studies
Epigenome‐wide association studies (EWAS) are designed to characterise population‐level
epigenetic differences across the genome and link them to disease. Most commonly, they …
epigenetic differences across the genome and link them to disease. Most commonly, they …
[图书][B] Impressionable biologies: From the archaeology of plasticity to the sociology of epigenetics
M Meloni - 2019 - taylorfrancis.com
During the twentieth century, genes were considered the controlling force of life processes,
and the transfer of DNA the definitive explanation for biological heredity. Such views shaped …
and the transfer of DNA the definitive explanation for biological heredity. Such views shaped …
Impact of alcohol exposure on neural development and network formation in human cortical organoids
JW Adams, PD Negraes, J Truong, T Tran… - Molecular …, 2023 - nature.com
Prenatal alcohol exposure is the foremost preventable etiology of intellectual disability and
leads to a collection of diagnoses known as Fetal Alcohol Spectrum Disorders (FASD) …
leads to a collection of diagnoses known as Fetal Alcohol Spectrum Disorders (FASD) …
DNA methylation signature of human fetal alcohol spectrum disorder
E Portales-Casamar, AA Lussier, MJ Jones… - Epigenetics & …, 2016 - Springer
Background Prenatal alcohol exposure is the leading preventable cause of behavioral and
cognitive deficits, which may affect between 2 and 5% of children in North America. While …
cognitive deficits, which may affect between 2 and 5% of children in North America. While …
Epigenetics of autism spectrum disorder
MT Siu, R Weksberg - Neuroepigenomics in aging and disease, 2017 - Springer
Autism spectrum disorder (ASD), one of the most common childhood neurodevelopmental
disorders (NDDs), is diagnosed in 1 of every 68 children. ASD is incredibly heterogeneous …
disorders (NDDs), is diagnosed in 1 of every 68 children. ASD is incredibly heterogeneous …
Prenatal influences on temperament development: The role of environmental epigenetics
MA Gartstein, MK Skinner - Development and Psychopathology, 2018 - cambridge.org
This review summarizes current knowledge and outlines future directions relevant to
questions concerning environmental epigenetics and the processes that contribute to …
questions concerning environmental epigenetics and the processes that contribute to …
DNA methylation as a predictor of fetal alcohol spectrum disorder
AA Lussier, AM Morin, JL MacIsaac, J Salmon… - Clinical …, 2018 - Springer
Background Fetal alcohol spectrum disorder (FASD) is a developmental disorder that
manifests through a range of cognitive, adaptive, physiological, and neurobiological deficits …
manifests through a range of cognitive, adaptive, physiological, and neurobiological deficits …