Regulation of neural circuit formation by protocadherins

SL Peek, KM Mah, JA Weiner - Cellular and molecular life sciences, 2017 - Springer
The protocadherins (Pcdhs), which make up the most diverse group within the cadherin
superfamily, were first discovered in the early 1990s. Data implicating the Pcdhs, including …

The molecular mechanisms of adaptive response related to environmental stress

A Rossnerova, A Izzotti, A Pulliero, A Bast… - International journal of …, 2020 - mdpi.com
The exposure of living organisms to environmental stress triggers defensive responses
resulting in the activation of protective processes. Whenever the exposure occurs at low …

Alcohol metabolism contributes to brain histone acetylation

P Mews, G Egervari, R Nativio, S Sidoli, G Donahue… - Nature, 2019 - nature.com
Emerging evidence suggests that epigenetic regulation is dependent on metabolic state,
and implicates specific metabolic factors in neural functions that drive behaviour. In neurons …

Estimation of a significance threshold for epigenome‐wide association studies

A Saffari, MJ Silver, P Zavattari, L Moi… - Genetic …, 2018 - Wiley Online Library
Epigenome‐wide association studies (EWAS) are designed to characterise population‐level
epigenetic differences across the genome and link them to disease. Most commonly, they …

[图书][B] Impressionable biologies: From the archaeology of plasticity to the sociology of epigenetics

M Meloni - 2019 - taylorfrancis.com
During the twentieth century, genes were considered the controlling force of life processes,
and the transfer of DNA the definitive explanation for biological heredity. Such views shaped …

Impact of alcohol exposure on neural development and network formation in human cortical organoids

JW Adams, PD Negraes, J Truong, T Tran… - Molecular …, 2023 - nature.com
Prenatal alcohol exposure is the foremost preventable etiology of intellectual disability and
leads to a collection of diagnoses known as Fetal Alcohol Spectrum Disorders (FASD) …

DNA methylation signature of human fetal alcohol spectrum disorder

E Portales-Casamar, AA Lussier, MJ Jones… - Epigenetics & …, 2016 - Springer
Background Prenatal alcohol exposure is the leading preventable cause of behavioral and
cognitive deficits, which may affect between 2 and 5% of children in North America. While …

Epigenetics of autism spectrum disorder

MT Siu, R Weksberg - Neuroepigenomics in aging and disease, 2017 - Springer
Autism spectrum disorder (ASD), one of the most common childhood neurodevelopmental
disorders (NDDs), is diagnosed in 1 of every 68 children. ASD is incredibly heterogeneous …

Prenatal influences on temperament development: The role of environmental epigenetics

MA Gartstein, MK Skinner - Development and Psychopathology, 2018 - cambridge.org
This review summarizes current knowledge and outlines future directions relevant to
questions concerning environmental epigenetics and the processes that contribute to …

DNA methylation as a predictor of fetal alcohol spectrum disorder

AA Lussier, AM Morin, JL MacIsaac, J Salmon… - Clinical …, 2018 - Springer
Background Fetal alcohol spectrum disorder (FASD) is a developmental disorder that
manifests through a range of cognitive, adaptive, physiological, and neurobiological deficits …