Knowledge of the nature, prognosis, and ways to treat brain lesions in neonatal infants has
increased remarkably. Neonatal hypoxic-ischaemic encephalopathy (HIE) in term infants …

Neonatal seizures are an important example of an age-specific seizure syndrome.
Compared with seizures at older ages, neonatal seizures differ in etiology, semiology, and …

METHODS: The study was a multicenter, randomized, blinded, controlled, phase IIb trial
investigating the efficacy and safety of levetiracetam compared with phenobarbital as a first …

This article offers the preferred methods and indications for longterm, conventional
electroencephalography (EEG) monitoring for selected, high-risk neonates of postmenstrual …

Neonatal seizures are a common emergency in the neonatal intensive care unit (NICU).
There are many questions yet to be answered regarding the temporal/spatial characteristics …

Background Preclinical data suggest that the loop-diuretic bumetanide might be an effective
treatment for neonatal seizures. We aimed to assess dose and feasibility of intravenous …

Objective In the absence of controlled trials, treatment of neonatal seizures has changed
minimally despite poor drug efficacy. We tested bumetanide added to phenobarbital to treat …

Neonates are at especially high risk for seizures as compared to other age groups. 1 The
high risk for seizures—and especially acute symptomatic seizures—is likely multifactorial …

PURPOSE: Neonatal seizures are common, especially in prematurity. Phenobarbital (PB)
currently represents the antiepileptic drug (AED) of choice, despite being related to …

Neonatal seizures are often refractory to treatment with initial antiseizure medications.
Consequently, clinicians turn to alternatives such as levetiracetam, despite the lack of …