Introduction 3. Materials and Methods 3.1. Reagents 3.2. Cell culture and treatment 3.3.
Cytotoxicity assay 3.4. Cell growth assay 3.5. Colony formation assay 3.6. Detection of …

Background Androgen deprivation therapy is the primary strategy for the treatment of
advanced prostate cancer; however, after an initial regression, most patients will inevitably …

Radiation therapy is a first-line treatment option for localized prostate cancer and radiation-
induced normal tissue damage are often the main limiting factor for modern radiotherapy …

The present invention relates to compositions and methods for cancer diagnosis, research
and therapy, including but not limited to, cancer markers. In particular, the present invention …

Abstract 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD; dioxin) is a toxic environmental
contaminant that works through dioxin response elements (DRE) to activate gene …

Intrauterine growth restriction (IUGR) is associated with detrimental effects on
neurodevelopmental progress in childhood and higher risk of degenerative diseases in …

Single nucleotide polymorphisms (SNPs) occurring in noncoding sequences have largely
been ignored in genome‐wide association studies (GWAS). Yet, amounting evidence …

Abstract Recent US Food and Drug Administration approval of the first immunotherapy for
prostate cancer encourages efforts to improve immune targeting of this disease. The …

Estrogen Receptor‐β (ER‐β), a tumor‐suppressor in prostate cancer, is epigenetically
repressed by hypermethylation of its promoter. DNA‐methyltransferases (DNMTs), which …

OBJECTIVE: The p15INK4B tumor suppressor is frequently silenced by promoter
hypermethylation in myelodysplastic syndrome and acute myeloid leukemia (AML) …