Chronic diseases account for over 60% of all deaths worldwide according to the World
Health Organization reports. Majority of cases are triggered by environmental exposures that …

Hepatocellular carcinoma harbors numerous genomic and epigenomic aberrations of DNA
copy numbers and DNA methylation. Transcriptomic deregulation by these aberrations plays …

To identify new tumor‐suppressor gene candidates relevant for human
hepatocarcinogenesis, we performed genome‐wide methylation profiling and vertical …

Many nutrients are known for a wide range of activities in prevention and alleviation of
various diseases. Recently, their potential role in regulating human health through effects on …

Nutrigenomics is a study of how the genes and diet of a person interact. An individual's diet
regime can drive gene regulation and its downstream ultimatum towards health illness …

Changes in brain structure and cortical function are associated with many chronic pain
conditions including low back pain and fibromyalgia. The magnitude of these changes …

Abstract Changes in gene expression that reset a cell program from a normal to a diseased
state involve multiple genetic circuitries, creating a characteristic signature of gene …

Background Breast cancer is the most frequent localization of malignant process in
American women and women of European countries. To date it is not possible to control the …

Hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide.
Despite advances in the diagnosis and treatment of HCC, incidence, and mortality continue …

Novel insights into the epigenetic control of chronic liver diseases are now emerging.
Recent advances in our understanding of the critical roles of DNA methylation, histone …