In the last decade, epigenetic drugs (such as inhibitors of DNA methyltransferases and
histone deacetylases) have been intensively used for cancer treatment. Their applications …

Chronic pain is a prevalent condition with a multifaceted pathogenesis, where epigenetic
modifications, particularly DNA methylation, might play an important role. This review delves …

Hepatocellular carcinoma (HCC) is the third most common cause of cancer death
worldwide. Hepatocarcinogenesis is a complex, multistep process. It is now recognized that …

Hepatitis C virus (HCV)/human immunodeficiency virus (HIV) co-infection still involves 2.3
million patients worldwide of the estimated 37.7 million living with HIV, according to World …

Sarcomas comprise a large number of rare, histogenetically heterogeneous, mesenchymal
tumors. Cancers such as Ewing's sarcoma, liposarcoma, rhabdomyosarcoma and synovial …

Bisulfite sequencing is considered as the gold standard approach for measuring DNA
methylation, which acts as a pivotal part in regulating a variety of biological processes …

Oral squamous cell carcinoma (OSCC), the most frequent of all oral cancers, is a type of
highly malignant tumors with a high capacity to invade locally and form distant metastases …

Background Abnormal expression of splicing factor 3A subunit 3 (SF3A3), a component of
the spliceosome, has been confirmed to be related to the occurrence and development of …

Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-
associated deaths worldwide. Although recent studies have proposed different biomarkers …

Background Hepatocellular carcinoma (HCC) is a malignancy with poor prognosis. Complex
genetic and epigenetic alterations are the two primary causes of HCC. The aim of the study …