The impact of maternal high-fat diet on offspring neurodevelopment
G Urbonaite, A Knyzeliene, FS Bunn… - Frontiers in …, 2022 - frontiersin.org
A maternal high-fat diet affects offspring neurodevelopment with long-term consequences on
their brain health and behavior. During the past three decades, obesity has rapidly …
their brain health and behavior. During the past three decades, obesity has rapidly …
A comprehensive approach to modeling maternal immune activation in rodents
MC Bucknor, A Gururajan, RC Dale… - Frontiers in …, 2022 - frontiersin.org
Prenatal brain development is a highly orchestrated process, making it a very vulnerable
window to perturbations. Maternal stress and subsequent inflammation during pregnancy …
window to perturbations. Maternal stress and subsequent inflammation during pregnancy …
[HTML][HTML] Habitual daily intake of a sweet and fatty snack modulates reward processing in humans
SE Thanarajah, AG DiFeliceantonio, K Albus… - Cell metabolism, 2023 - cell.com
Western diets rich in fat and sugar promote excess calorie intake and weight gain; however,
the underlying mechanisms are unclear. Despite a well-documented association between …
the underlying mechanisms are unclear. Despite a well-documented association between …
High-fat food biases hypothalamic and mesolimbic expression of consummatory drives
Maintaining healthy body weight is increasingly difficult in our obesogenic environment.
Dieting efforts are often overpowered by the internal drive to consume energy-dense foods …
Dieting efforts are often overpowered by the internal drive to consume energy-dense foods …
Prolonged breastfeeding protects from obesity by hypothalamic action of hepatic FGF21
V Pena-Leon, C Folgueira, S Barja-Fernández… - Nature …, 2022 - nature.com
Early-life determinants are thought to be a major factor in the rapid increase of obesity.
However, while maternal nutrition has been extensively studied, the effects of breastfeeding …
However, while maternal nutrition has been extensively studied, the effects of breastfeeding …
Female aging: when translational models don't translate
For many pathologies associated with aging, female patients present with higher morbidity
and more frequent adverse events from treatments compared to male patients. While …
and more frequent adverse events from treatments compared to male patients. While …
AgRP neurons coordinate the mitigation of activity-based anorexia
AK Sutton Hickey, SC Duane, LE Mickelsen… - Molecular …, 2023 - nature.com
Anorexia nervosa (AN) is a debilitating and deadly disease characterized by low body mass
index due to diminished food intake, and oftentimes concurrent hyperactivity. A high …
index due to diminished food intake, and oftentimes concurrent hyperactivity. A high …
Neurodevelopmental programming of adiposity: contributions to obesity risk
AA Skowronski, RL Leibel, CA LeDuc - Endocrine Reviews, 2024 - academic.oup.com
This review analyzes the published evidence regarding maternal factors that influence the
developmental programming of long-term adiposity in humans and animals via the central …
developmental programming of long-term adiposity in humans and animals via the central …
Can breastfeeding affect the rest of our life?
The breastfeeding period is one of the most important critical windows in our development,
since milk, our first food after birth, contains several compounds, such as macronutrients …
since milk, our first food after birth, contains several compounds, such as macronutrients …
Mechanisms underlying the cognitive and behavioural effects of maternal obesity
The widespread consumption of 'western'-style diets along with sedentary lifestyles has led
to a global epidemic of obesity. Epidemiological, clinical and preclinical evidence suggests …
to a global epidemic of obesity. Epidemiological, clinical and preclinical evidence suggests …