Biases in bioethics: a narrative review

B Hofmann - BMC medical ethics, 2023 - Springer
Given that biases can distort bioethics work, it has received surprisingly little and fragmented
attention compared to in other fields of research. This article provides an overview of …

Genetic disease and therapy

TL Roth, A Marson - Annual Review of Pathology: Mechanisms …, 2021 - annualreviews.org
Genetic diseases cause numerous complex and intractable pathologies. DNA sequences
encoding each human's complexity and many disease risks are contained in the …

Germline genome editing versus preimplantation genetic diagnosis: Is there a case in favour of germline interventions?

R Ranisch - Bioethics, 2020 - Wiley Online Library
CRISPR is widely considered to be a disruptive technology. However, when it comes to the
most controversial topic, germline genome editing (GGE), there is no consensus on whether …

Genome editing and assisted reproduction: curing embryos, society or prospective parents?

G Cavaliere - Medicine, health care and philosophy, 2018 - Springer
This paper explores the ethics of introducing genome-editing technologies as a new
reproductive option. In particular, it focuses on whether genome editing can be considered a …

[图书][B] Medical ethics: a very short introduction

M Dunn, T Hope - 2018 - books.google.com
The issue of medical ethics, from thorny moral questions such as euthanasia and the
morality of killing to political questions such as the fair distribution of health care resources …

Human germline genome editing: On the nature of our reasons to genome edit

R Sparrow - The American Journal of Bioethics, 2022 - Taylor & Francis
Ever since the publication of Derek Parfit's Reasons and Persons, bioethicists have tended
to distinguish between two different ways in which reproductive technologies may have …

Home-based cognitively assistive robots: maximizing cognitive functioning and maintaining independence in older adults without dementia

R Van Patten, AV Keller, JE Maye… - … interventions in aging, 2020 - Taylor & Francis
Promoting health and prolonging independence in the home is a priority for older adults,
caregivers, clinicians, and society at large. Rapidly developing robotics technology provides …

[HTML][HTML] Superior retinal gene transfer and biodistribution profile of subretinal versus intravitreal delivery of AAV8 in nonhuman primates

IP Seitz, S Michalakis, B Wilhelm… - … & visual science, 2017 - tvst.arvojournals.org
Purpose: To investigate shedding and biodistribution characteristics of recombinant adeno-
associated virus serotype 8 (rAAV8) after single-dose subretinal or intravitreal injection in …

Beyond safety: mapping the ethical debate on heritable genome editing interventions

M Almeida, R Ranisch - Humanities and Social Sciences …, 2022 - nature.com
Genetic engineering has provided humans the ability to transform organisms by direct
manipulation of genomes within a broad range of applications including agriculture (eg, GM …

Moral reasons to edit the human genome: picking up from the Nuffield report

C Gyngell, H Bowman-Smart, J Savulescu - Journal of medical ethics, 2019 - jme.bmj.com
In July 2018, the Nuffield Council of Bioethics released its long-awaited report on heritable
genome editing (HGE). The Nuffield report was notable for finding that HGE could be morally …