Physical activity (PA) has been central in the life of our species for most of its history, and
thus shaped our physiology during evolution. However, only recently the health …

Pioneering studies performed over the past few decades demonstrate links between
epigenetics and type 2 diabetes mellitus (T2DM), the metabolic disorder with the most …

Cardiovascular diseases (CVD), including heart and pathological circulatory conditions, are
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …

Physical activity is a strong stimulus influencing the overall physiology of the human body.
Exercises lead to biochemical changes in various tissues and exert an impact on gene …

Oxidative stress can be induced by various stimuli and altered in certain conditions,
including exercise and pain. Although many studies have investigated oxidative stress in …

Abstract Changes in gene expression are involved in many brain functions. Epigenetic
processes modulate gene expression by histone modification and DNA methylation or RNA …

Aging causes degenerative changes such as epigenetic changes and mitochondrial
dysfunction in skeletal muscle. Exercise can upregulate muscle mitochondrial homeostasis …

The combination of multiple omics approaches has emerged as an innovative holistic scope
to provide a more comprehensive view of the molecular and physiological events underlying …

Non-alcoholic fatty liver disease (NAFLD) is highly prevalent in Western countries and has
become a serious public health concern. Although Western-style dietary patterns …

The Mediterranean diet is a healthy dietary pattern whose main characteristic is olive oil
consumption. The potential health benefits of olive oil have been extensively investigated …