Reprogramming mammalian somatic cells
Somatic cell nuclear transfer (SCNT), the technique commonly known as cloning, permits
transformation of a somatic cell into an undifferentiated zygote with the potential to develop …
transformation of a somatic cell into an undifferentiated zygote with the potential to develop …
Can reprogramming of overall epigenetic memory and specific parental genomic imprinting memory within donor cell-inherited nuclear genome be a major hindrance …
M Samiec, M Skrzyszowska - Annals of Animal Science, 2018 - sciendo.com
Department of Reproductive Biotechnology and Cryoconservation, National Research
Institute of Animal Production, 32-083 Balice n. Kraków, Poland♦ Corresponding author …
Institute of Animal Production, 32-083 Balice n. Kraków, Poland♦ Corresponding author …
Sperm-borne miR-449b influences cleavage, epigenetic reprogramming and apoptosis of SCNT embryos in bovine
M Wang, Y Gao, P Qu, S Qing, F Qiao, Y Zhang… - Scientific Reports, 2017 - nature.com
Accumulating evidence indicates the absence of paternally derived miRNAs, piwiRNAs, and
proteins may be one important factor contributing to developmental failure in somatic cell …
proteins may be one important factor contributing to developmental failure in somatic cell …
Effects of DNMT1 and HDAC Inhibitors on Gene-Specific Methylation Reprogramming during Porcine Somatic Cell Nuclear Transfer
W Xu, Z Li, B Yu, X He, J Shi, R Zhou, D Liu, Z Wu - PloS one, 2013 - journals.plos.org
Somatic cell nuclear transfer (SCNT) in mammalian cloning currently remains inefficient.
Incomplete or erroneous epigenetic reprogramming of specialized donor somatic nuclear …
Incomplete or erroneous epigenetic reprogramming of specialized donor somatic nuclear …
Melatonin significantly improves the developmental competence of bovine somatic cell nuclear transfer embryos
J Su, Y Wang, X Xing, L Zhang, H Sun… - Journal of pineal …, 2015 - Wiley Online Library
Somatic cell nuclear transfer (SCNT) is a promising technology, but its application is
hampered by its low efficiency. Hence, the majority of SCNT embryos fail to develop to term …
hampered by its low efficiency. Hence, the majority of SCNT embryos fail to develop to term …
Oocytes selected using BCB staining enhance nuclear reprogramming and the in vivo development of SCNT embryos in cattle
J Su, Y Wang, R Li, H Peng, S Hua, Q Li, F Quan… - PloS one, 2012 - journals.plos.org
The selection of good quality oocytes is crucial for in vitro fertilization and somatic cloning.
Brilliant cresyl blue (BCB) staining has been used for selection of oocytes from several …
Brilliant cresyl blue (BCB) staining has been used for selection of oocytes from several …
Oxamflatin Significantly Improves Nuclear Reprogramming, Blastocyst Quality, and In Vitro Development of Bovine SCNT Embryos
Aberrant epigenetic nuclear reprogramming results in low somatic cloning efficiency.
Altering epigenetic status by applying histone deacetylase inhibitors (HDACi) enhances …
Altering epigenetic status by applying histone deacetylase inhibitors (HDACi) enhances …
Sperm-borne miR-202 targets SEPT7 and regulates first cleavage of bovine embryos via cytoskeletal remodeling
M Wang, Y Du, S Gao, Z Wang, P Qu, Y Gao… - …, 2021 - journals.biologists.com
In mammals, sperm-borne regulators can be transferred to oocytes during fertilization and
have different effects on the formation of pronuclei, the first cleavage of zygotes, the …
have different effects on the formation of pronuclei, the first cleavage of zygotes, the …
Expression of pluripotency‐related genes is highly dependent on trichostatin A‐assisted epigenomic modulation of porcine mesenchymal stem cells analysed for …
M Samiec, J Romanek, D Lipiński… - Animal Science …, 2019 - Wiley Online Library
The present study sought to examine whether trichostatin A (TSA)‐assisted epigenetic
transformation of porcine bone marrow (BM)‐derived mesenchymal stem cells (BM‐MSCs) …
transformation of porcine bone marrow (BM)‐derived mesenchymal stem cells (BM‐MSCs) …
[HTML][HTML] DNA methylation mediated down-regulation of ANGPTL4 promotes colorectal cancer metastasis by activating the ERK pathway
K Zhang, Z Zhai, S Yu, Y Tao - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Background: Colorectal cancer (CRC) imposes significant health burden and is increasing
in incidence. NGPTL4 has been implicated in the development of CRC. The present study …
in incidence. NGPTL4 has been implicated in the development of CRC. The present study …