The behaviour and ecology of the zebrafish, Danio rerio
The zebrafish Danio rerio, is an important model organism in developmental genetics,
neurophysiology and biomedicine, but little is known about its natural ecology and …
neurophysiology and biomedicine, but little is known about its natural ecology and …
Headwaters of the zebrafish—emergence of a new model vertebrate
DJ Grunwald, JS Eisen - Nature reviews genetics, 2002 - nature.com
The understanding of vertebrate development has advanced considerably in recent years,
primarily due to the study of a few model organisms. The zebrafish, the newest of these …
primarily due to the study of a few model organisms. The zebrafish, the newest of these …
Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ
M Yuan, N Konstantopoulos, J Lee, L Hansen, ZW Li… - Science, 2001 - science.org
We show that high doses of salicylates reverse hyperglycemia, hyperinsulinemia, and
dyslipidemia in obese rodents by sensitizing insulin signaling. Activation or overexpression …
dyslipidemia in obese rodents by sensitizing insulin signaling. Activation or overexpression …
The state of the art of the zebrafish model for toxicology and toxicologic pathology research—advantages and current limitations
JM Spitsbergen, ML Kent - Toxicologic pathology, 2003 - journals.sagepub.com
The zebrafish (Danio rerio) is now the pre-eminent vertebrate model system for clarification
of the roles of specific genes and signaling pathways in development. The zebrafish …
of the roles of specific genes and signaling pathways in development. The zebrafish …
[HTML][HTML] The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension
J Topczewski, DS Sepich, DC Myers, C Walker… - Developmental cell, 2001 - cell.com
Mutations in the zebrafish knypek locus impair gastrulation movements of convergent
extension that narrow embryonic body and elongate it from head to tail. We demonstrate that …
extension that narrow embryonic body and elongate it from head to tail. We demonstrate that …
Life spans and senescent phenotypes in two strains of Zebrafish (Danio rerio)
GS Gerhard, EJ Kauffman, X Wang, R Stewart… - Experimental …, 2002 - Elsevier
Zebrafish have become a widely used model organism in developmental biology research.
In order to initiate an experimental foundation for aging studies, we have determined some …
In order to initiate an experimental foundation for aging studies, we have determined some …
[HTML][HTML] Fibronectin regulates epithelial organization during myocardial migration in zebrafish
LA Trinh, DYR Stainier - Developmental cell, 2004 - cell.com
Several genes have been implicated in heart tube formation, yet we know little about
underlying cellular mechanisms. We analyzed the cellular architecture of the migrating …
underlying cellular mechanisms. We analyzed the cellular architecture of the migrating …
Cultured adult cardiac myocytes: future applications, culture methods, morphological and electrophysiological properties
JS Mitcheson, JC Hancox, AJ Levi - Cardiovascular research, 1998 - academic.oup.com
Isolated adult cardiac myocytes maintained in primary culture have been used as a model of
the adult myocardium for 20 years. With the recent advances and current interest in using …
the adult myocardium for 20 years. With the recent advances and current interest in using …
[HTML][HTML] Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation
J Zhang, WS Talbot, AF Schier - Cell, 1998 - cell.com
The zebrafish one-eyed pinhead (oep) mutation disrupts embryonic development, resulting
in cyclopia and defects in endoderm, prechordal plate, and ventral neuroectoderm …
in cyclopia and defects in endoderm, prechordal plate, and ventral neuroectoderm …
UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish
EC Walsh, DYR Stainier - Science, 2001 - science.org
Cardiac valve formation is a complex process that involves cell signaling events between
the myocardial and endocardial layers of the heart across an elaborate extracellular matrix …
the myocardial and endocardial layers of the heart across an elaborate extracellular matrix …