Antibodies play a vital role in the immune response to infectious diseases and can be
administered passively to protect patients. In the case of Cryptococcus neoformans, a WHO …

A convergent synthetic strategy to Cryptococcus neoformans glucuronoxylomannan (GXM)
capsular polysaccharide part structures was developed based on di-, tri-, tetra-, penta-and …

Classic antibody functions include opsonization, complement activation, and enhancement
of cellular antimicrobial function. Antibodies can also have catalytic activity, although the …

Cryptococcus neoformans and Cryptococcus gattii are pathogenic fungi that cause
significant morbidity and mortality. Cell surface hydrophobicity (CSH) is a biophysical …

The polysaccharide capsule of fungal pathogen Cryptococcus neoformans is a critical
virulence factor that has historically evaded complete characterization. Cryptococcal …

In cerebral cryptococcomas caused by Cryptococcus neoformans or Cryptococcus gattii, the
density of fungal cells within lesions can contribute to the overall brain fungal burden. In …

Cryptococcus neoformans is an opportunistic fungal pathogen, which is a frequent cause of
a life-threatening meningitis in immunocompromised individuals. We report the first total …

Microbial polysaccharide characterization requires purification that often involves detergent
precipitation and lyophilization. Here we examined physicochemical changes following …

Cryptococcus neoformans is a human fungal pathogen responsible for fatal infections,
especially in patients with a depressed immune system. Overexposure to antifungal drugs …

Cryptococcus neoformans is a fungal pathogen responsible for> 200,000 yearly cases with
a mortality as high as 81%. This burden results, in part, from an incomplete understanding of …