Simple Summary According to the available data, colorectal cancer (CRC) is one of the most
common malignant neoplasms. Depending on the location, type of cancer or gender, it is …

The incidence of cancer, adjusted for secular trends, is directly related to age, and advanced
chronologic age is one of the most significant risk factors for cancer. Organismal aging is …

Background Given the differences in embryonic origin, vascular and nervous supplies,
microbiotic burden, and main physiological functions of left and right colons, tumor location …

Colorectal cancer (CRC) is among the most common cancers. In fact, it is placed in the third
place among the most diagnosed cancer in men, after lung and prostate cancer, and in the …

Epigenetic alterations play a key role in the initiation and progression of cancer. Therefore, it
is possible to use epigenetic marks as biomarkers for predictive and precision medicine in …

Colorectal cancer (CRC) is one of the most prevalent cancers that threaten people in many
countries. It is a multi-factorial chronic disease caused by a combination of genetic and …

Colorectal cancer (CRC) is the third most prevalent cancer in the world. Globally, it has been
estimated that about 1.4 million new cases of colorectal cancer are diagnosed every year …

Abstract Each year, almost 4.1 million people are diagnosed with gastrointestinal (GI)
cancers. Due to late detection of this disease, the mortality is high, causing approximately 3 …

Over the last years, epigenetic changes, including DNA methylation and histone
modifications detected in early tumorigenesis and cancer progression, have been proposed …

Purpose Methylated cell-free DNA in liquid biopsies are promising non-invasive biomarkers
for colorectal cancer (CRC). Optimal markers would have high sensitivity and specificity for …