Pathophysiology of sarcopenia: genetic factors and their interplay with environmental factors

AM Aslam, EB Ma, JY Huh - Metabolism, 2023 - Elsevier
Sarcopenia is a geriatric disorder characterized by a progressive decline in muscle mass
and function. This disorder has been associated with a range of adverse health outcomes …

[HTML][HTML] Circulating inflammatory biomarker responses in intervention trials in frail and sarcopenic older adults: a systematic review and meta-analysis

T Byrne, J Cooke, P Bambrick, E McNeela… - Experimental …, 2023 - Elsevier
Consistent with the inflammaging concept, cross-sectional associations have been
established between inflammatory biomarkers, frailty and sarcopenia. Less certain is the …

Sarcopenia: still in relative definition-penia and severe treatment-penia

SA Polyzos, CS Mantzoros - Metabolism, 2023 - Elsevier
Sarcopenia derives from the Greek words “sarx”(ie, flesh) and “penia”(ie, deficiency), and
denotes the decline in the quantity (ie, number of motor units) and quality (atrophy of muscle …

[HTML][HTML] Sarcopenia as a little-recognized comorbidity of type II diabetes mellitus: a review of the diagnosis and treatment

C Salom Vendrell, E García Tercero… - Nutrients, 2023 - mdpi.com
Background: Type II diabetes mellitus (T2DM) is one of the most widespread metabolic
diseases worldwide, with a significant impact on morbi-mortality. Sarcopenia has a high risk …

The Interconnection Between Muscle and Bone: A Common Clinical Management Pathway

C Smith, M Sim, J Dalla Via, I Levinger… - Calcified Tissue …, 2024 - Springer
Often observed with aging, the loss of skeletal muscle (sarcopenia) and bone (osteoporosis)
mass, strength, and quality, is associated with reduced physical function contributing to falls …

Muscle mass, creatinine, cystatin C and selective glomerular hypofiltration syndromes

L Malmgren, A Grubb - Clinical Kidney Journal, 2023 - academic.oup.com
In this issue of Clinical Kidney Journal, Stehlé and colleagues demonstrate that estimation of
glomerular filtration rate (GFR) by use of creatinine and a measure, total lumbar muscle …

Azilsartan ameliorates skeletal muscle wasting in high fat diet (HFD)-induced sarcopenic obesity in rats via activating Akt signalling pathway

P Prajapati, A Kumar, J Singh, SA Saraf… - Archives of Gerontology …, 2023 - Elsevier
An association between the loss of skeletal muscle mass and obesity in the geriatric
population has been identified as a disease known as sarcopenic obesity. Therefore …

Comparison of the serum creatinine-and cystatin-C–based indices as screening biomarkers for sarcopenia in community-dwelling older adults

JY Jang, HE Shin, CW Won, M Kim - Archives of Gerontology and Geriatrics, 2023 - Elsevier
Background Several creatinine-and cystatin-C–based indices have been proposed as
sarcopenia predictors. This study aimed to compare serum creatinine-and cystatin-C–based …

[HTML][HTML] Spectrochemical analysis of blood combined with chemometric techniques for detecting osteosarcopenia

TG da Silva, CLM Morais, MCD Santos, LAS de Lima… - Scientific Reports, 2023 - nature.com
Among several complications related to physiotherapy, osteosarcopenia is one of the most
frequent in elderly patients. This condition is limiting and quite harmful to the patient's health …

[HTML][HTML] Neurofilament-light chains (NF-L), a biomarker of neuronal damage, is increased in patients with severe sarcopenia: results of the SarcoPhAge study

A Ladang, S Kovacs, L Lengelé, M Locquet… - Aging Clinical and …, 2023 - Springer
Background As clinical tests, such as gait speed, require nervous system integrity to be
performed properly, sarcopenia shares features with neurological diseases. Neurofilament …