Metabolic reprogramming and epigenetic modifications on the path to cancer
L Sun, H Zhang, P Gao - Protein & cell, 2022 - academic.oup.com
Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally
regulate each other, are among the well-known cancer hallmarks. Recent evidence …
regulate each other, are among the well-known cancer hallmarks. Recent evidence …
[HTML][HTML] Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome
R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
Obstructive sleep apnea, hypoxia, and nonalcoholic fatty liver disease
Recent studies have demonstrated that obstructive sleep apnea (OSA) is associated with the
development and evolution of nonalcoholic fatty liver disease (NAFLD), independent of …
development and evolution of nonalcoholic fatty liver disease (NAFLD), independent of …
[HTML][HTML] Endothelial dysfunction driven by hypoxia—the influence of oxygen deficiency on NO bioavailability
A Janaszak-Jasiecka, A Siekierzycka, A Płoska… - Biomolecules, 2021 - mdpi.com
Cardiovascular diseases (CVDs) are the leading cause of death worldwide. The initial stage
of CVDs is characterized by endothelial dysfunction, defined as the limited bioavailability of …
of CVDs is characterized by endothelial dysfunction, defined as the limited bioavailability of …
Brain‐derived neurotrophic factor and post‐stroke depression
E Zhang, P Liao - Journal of neuroscience research, 2020 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is well known to play a critical role in cognition. Its
role in mood disorders, including post stroke depression (PSD), is also recognized with …
role in mood disorders, including post stroke depression (PSD), is also recognized with …
The potential of hyperbaric oxygen as a therapy for neurodegenerative diseases
P Mensah-Kane, N Sumien - GeroScience, 2023 - Springer
Abstract The World Health Organization estimates that by the year 2040, neurodegenerative
diseases will be the second leading cause of death in developed countries, overtaking …
diseases will be the second leading cause of death in developed countries, overtaking …
Carotid body hypersensitivity in intermittent hypoxia and obtructive sleep apnoea
NR Prabhakar, YJ Peng, J Nanduri - The Journal of Physiology, 2023 - Wiley Online Library
Carotid bodies are the principal sensory organs for detecting changes in arterial blood
oxygen concentration, and the carotid body chemoreflex is a major regulator of the …
oxygen concentration, and the carotid body chemoreflex is a major regulator of the …
[HTML][HTML] Hypoxia: molecular pathophysiological mechanisms in human diseases
Y Della Rocca, L Fonticoli, TS Rajan, O Trubiani… - Journal of physiology …, 2022 - Springer
Hypoxia, a low O2 tension, is a fundamental feature that occurs in physiological events as
well as pathophysiological conditions, especially mentioned for its role in the mechanism of …
well as pathophysiological conditions, especially mentioned for its role in the mechanism of …
Rostral ventrolateral medulla and hypertension
PG Guyenet, RL Stornetta, BB Holloway… - …, 2018 - Am Heart Assoc
560 Hypertension September 2018 of interest in the potential contribution of sympatho-
respiratory coupling to SNA elevation in neurogenic hypertension. As summarized below …
respiratory coupling to SNA elevation in neurogenic hypertension. As summarized below …
Maternal obesity increases DNA methylation and decreases RNA methylation in the human placenta
WB Shen, J Ni, R Yao, KR Goetzinger, C Harman… - Reproductive …, 2022 - Elsevier
Maternal obesity is associated with increased risk of adverse pregnancy and birth outcomes.
While increasing body of evidence supports that the etiology is related to fetal and placental …
While increasing body of evidence supports that the etiology is related to fetal and placental …