DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …

Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

The response to exercise training (trainability) has been shown to have a strong heritable
component. There is growing evidence suggesting that traits such as trainability do not only …

Arsenic is a nonmutagenic human carcinogen that induces tumors through unknown
mechanisms. A growing body of evidence suggests that its carcinogenicity results from …

Plant DNA methylation is its own language, interpreted by the cell to maintain silencing of
transposons, facilitate chromatin structure, and to ensure proper expression of some genes …

The prospect of finding epigenetic risk factors for complex diseases would be greatly
enhanced if DNA from existing biobanks, which is generally extracted from whole blood …

Molecular subtypes-based therapies offer new potential framework for desired and precise
outcome in clinical settings. Current treatment strategies in colorectal cancer are largely 'one …

Accumulating evidence suggests that epigenetic alterations play an important role in
chemically-induced carcinogenesis. Although the epigenome and genome may be equally …

DNA methylation plays a critical role in genome function both in health and disease. Almost
60 years after the discovery of 5-methyl cytosine and∼ 25 years since the discovery that …

People differ in their requirements for and responses to nutrients and bioactive molecules in
the diet. Many inputs contribute to metabolic heterogeneity (including variations in genetics …