Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

Several new tests, as discussed in this review, have become available during the last 2
years. Although the intended use of most of these tests is to distinguish PCa from benign …

In epigenome-wide association studies, cell-type composition often differs between cases
and controls, yielding associations that simply tag cell type rather than reveal fundamental …

The proper identification of differentially methylated CpGs is central in most epigenetic
studies. The Illumina HumanMethylation450 BeadChip is widely used to quantify DNA …

Epigenetic modifications and regulators represent potential molecular elements which
control relevant physiological and pathological features, thereby contributing to the natural …

Background Breast cancer formation is associated with frequent changes in DNA
methylation but the extent of very early alterations in DNA methylation and the biological …

Sažetak Epigenetic mechanisms, such as DNA methylation, DNA hydroxymethylation, post-
translational modifications (PTMs) of histone proteins affecting nucleosome remodelling …

SRY-related high-mobility group box 9 (SOX9) is an indispensable transcription factor that
regulates multiple developmental pathways related to stemness, differentiation, and …

Epigenetics refers to the study of mechanisms able to influence gene expression in a stable
and potentially heritable manner without altering the DNA sequence. These mechanisms …

Epigenetics describes heritable alterations of gene expression and chromatin organization
without changes in DNA sequence. Both hypermethylation and hypomethylation of DNA can …