Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

Epigenetic modifications are increasingly recognized to play a role in the etiology and
pathophysiology of schizophrenia and other psychiatric disorders with developmental …

Given the difficulty of procuring human brain tissue, a key question in molecular psychiatry
concerns the extent to which epigenetic signatures measured in more accessible tissues …

There is a growing body of research focused on the relationship between childhood trauma
and the risk of developing psychosis. Numerous studies, including many large-scale …

Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms
that causes very significant disability in young people. While schizophrenia has a strong …

Recent studies suggest that genetic and environmental factors do not account for all the
schizophrenia risk, and epigenetics also has a role in disease susceptibility. DNA …

Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea,
identity, and emotions. It has no central pathophysiological mechanism and precise …

One of the major concerns of modern society is to identify putative biomarkers that serve as
a valuable early diagnostic tool to identify a subset of patients with increased risk to develop …

Importance Schizophrenia is a severe mental disorder in which epigenetic mechanisms may
contribute to illness risk. Epigenetic profiles can be derived from blood cells, but to our …

Accumulating evidence suggests that epigenetic alterations in brain-derived neurotrophic
factor (BDNF) promoters are associated with the pathophysiology of psychiatric disorders …