Diversity and evolution of B-family DNA polymerases
B-family DNA polymerases (PolBs) represent the most common replicases. PolB enzymes
that require RNA (or DNA) primed templates for DNA synthesis are found in all domains of …
that require RNA (or DNA) primed templates for DNA synthesis are found in all domains of …
Haloferax volcanii—a model archaeon for studying DNA replication and repair
P Pérez-Arnaiz, A Dattani, V Smith… - Open Biology, 2020 - royalsocietypublishing.org
The tree of life shows the relationship between all organisms based on their common
ancestry. Until 1977, it comprised two major branches: prokaryotes and eukaryotes. Work by …
ancestry. Until 1977, it comprised two major branches: prokaryotes and eukaryotes. Work by …
The replication machinery of LUCA: common origin of DNA replication and transcription
EV Koonin, M Krupovic, S Ishino, Y Ishino - BMC biology, 2020 - Springer
Origin of DNA replication is an enigma because the replicative DNA polymerases (DNAPs)
are not homologous among the three domains of life, Bacteria, Archaea, and Eukarya. The …
are not homologous among the three domains of life, Bacteria, Archaea, and Eukarya. The …
Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA
C Madru, G Henneke, P Raia… - Nature …, 2020 - nature.com
Replicative DNA polymerases (DNAPs) have evolved the ability to copy the genome with
high processivity and fidelity. In Eukarya and Archaea, the processivity of replicative DNAPs …
high processivity and fidelity. In Eukarya and Archaea, the processivity of replicative DNAPs …
A unique B-Family DNA polymerase facilitating error-prone DNA damage tolerance in crenarchaeota
X Feng, X Liu, R Xu, R Zhao, W Feng, J Liao… - Frontiers in …, 2020 - frontiersin.org
Sulfolobus islandicus codes for four DNA polymerases: three are of the B-family (Dpo1,
Dpo2, and Dpo3), and one is of the Y-family (Dpo4). Western analysis revealed that among …
Dpo2, and Dpo3), and one is of the Y-family (Dpo4). Western analysis revealed that among …
PolB1 Is Sufficient for DNA Replication and Repair Under Normal Growth Conditions in the Extremely Thermophilic Crenarchaeon Sulfolobus acidocaldarius
H Miyabayashi, R Jain, S Suzuki, DW Grogan… - Frontiers in …, 2020 - frontiersin.org
The thermophilic crenarchaeon Sulfolobus acidocaldarius has four DNA polymerases
(DNAPs): PolB1, PolB2, PolB3, and Dbh (PolY). Previous in vitro studies suggested that …
(DNAPs): PolB1, PolB2, PolB3, and Dbh (PolY). Previous in vitro studies suggested that …
Biochemical reconstitution and genetic characterization of the major oxidative damage base excision DNA repair pathway in Thermococcus kodakarensis
AM Gehring, KM Zatopek, BW Burkhart, V Potapov… - DNA repair, 2020 - Elsevier
Reactive oxygen species drive the oxidation of guanine to 8-oxoguanine (8oxoG), which
threatens genome integrity. The repair of 8oxoG is carried out by base excision repair …
threatens genome integrity. The repair of 8oxoG is carried out by base excision repair …
Family D DNA polymerase interacts with GINS to promote CMG-helicase in the archaeal replisome
K Oki, M Nagata, T Yamagami, T Numata… - Nucleic acids …, 2022 - academic.oup.com
Genomic DNA replication requires replisome assembly. We show here the molecular
mechanism by which CMG (GAN–MCM–GINS)-like helicase cooperates with the family D …
mechanism by which CMG (GAN–MCM–GINS)-like helicase cooperates with the family D …
Processing of matched and mismatched rNMPs in DNA by archaeal ribonucleotide excision repair
M Reveil, L Chapel, B Vourc'h, A Bossé, L Vialle… - Iscience, 2023 - cell.com
Ribonucleoside monophosphates (rNMPs) are the main non-canonical nucleotides in
genomic DNA, and their incorporation can occur as mismatches or matches in vivo. To …
genomic DNA, and their incorporation can occur as mismatches or matches in vivo. To …
Role of RadA and DNA polymerases in recombination-associated DNA synthesis in hyperthermophilic archaea
G Hogrel, Y Lu, N Alexandre, A Bossé, R Dulermo… - Biomolecules, 2020 - mdpi.com
Among the three domains of life, the process of homologous recombination (HR) plays a
central role in the repair of double-strand DNA breaks and the restart of stalled replication …
central role in the repair of double-strand DNA breaks and the restart of stalled replication …