Plasmodium falciparum: properties of an α-like DNA polymerase, the key enzyme in DNA synthesis
L Abu-Elheiga, DT Spira, U Bachrach - Experimental parasitology, 1990 - Elsevier
An α-like DNA polymerase has been identified and characterized in the extracts from the
malarial parasite Plasmodium falciparum. The enzyme is sensitive to the specific inhibitors …
malarial parasite Plasmodium falciparum. The enzyme is sensitive to the specific inhibitors …
Translesion replication in cisplatin-treated xeroderma pigmentosum variant cells is also caffeine-sensitive: features of the error-prone DNA polymerase (s) involved in …
K Yamada, J Takezawa, O Ezaki - DNA repair, 2003 - Elsevier
Patients with xeroderma pigmentosum variant (XP-V) have a higher risk to skin cancer and
XP-V cells are extremely mutable by ultraviolet (UV). The defective gene encodes a DNA …
XP-V cells are extremely mutable by ultraviolet (UV). The defective gene encodes a DNA …
Initiation of DNA Replication by Primer Proteins: Bacteriophage ø29 and Its Relatives
M Salas - The Molecular Biology of Bacterial Virus Systems, 1988 - Springer
The fact that none of the known DNA polymerases is able to initiate DNA chains but only to
elongate from a free 3'-OH group raises the problem of how replication is initiated, both at …
elongate from a free 3'-OH group raises the problem of how replication is initiated, both at …
Inhibition of herpes simplex virus type 1 DNA polymerase by [1R (1 alpha, 2 beta, 3 alpha)]-9-[2, 3-bis (hydroxymethyl) cyclobutyl] guanine.
BJ Terry, CW Cianci, ME Hagen - Molecular pharmacology, 1991 - ASPET
(+/-)-(1 alpha, 2 beta, 3 alpha)-9-[2, 3-Bis (hydroxymethyl) cyclobutyl] guanine [(+/-)-BHCG]
is a nucleoside analog with potent in vitro activity against herpesviruses [Tetrahedron Lett …
is a nucleoside analog with potent in vitro activity against herpesviruses [Tetrahedron Lett …
Resolution and purification of free primase activity from the DNA primase-poivmerase α complex of HeLa cells
JK Vishwanatha, EF Baril - Nucleic acids research, 1986 - academic.oup.com
DNA primase activlty has been resolved from a purified DNA primase-polymerase α
complex of HeLa cells by hydrophobia affinity chromatography on phenylSepharose …
complex of HeLa cells by hydrophobia affinity chromatography on phenylSepharose …
[HTML][HTML] Structural relationships between two forms of DNA polymerase epsilon from calf thymus.
G Siegal, JJ Turchi, CB Jessee, LM Mallaber… - Journal of Biological …, 1992 - Elsevier
We previously reported purification of two forms of DNA polymerase epsilon from calf thymus
(Crute, JJ, Wahl, AF, and Bambara, RA (1986) Biochemistry 25, 26-36). We have now used …
(Crute, JJ, Wahl, AF, and Bambara, RA (1986) Biochemistry 25, 26-36). We have now used …
Replication and Transcription of Bacteriophage ϕ29 DNA
M Salas, F Rojo - Bacillus subtilis and other Gram‐positive …, 1993 - Wiley Online Library
The genome of Bacillus subtilis phage Ø29 consists of a linear, double‐stranded DNA
19,285 bp long with a 6‐bp‐long inverted terminal repeat (AAAGTA; 32, 114) and a terminal …
19,285 bp long with a 6‐bp‐long inverted terminal repeat (AAAGTA; 32, 114) and a terminal …
[PDF][PDF] Two DNA polymerases from Trypanosoma cruzi: biochemical characterization and effects of inhibitors
C Rojas, J Venegas, S Litvak, A Solari - Comp Biochem Physiol, 1992 - academia.edu
l. Two DNA polymerases have been partially purified from zyxwvutsrqponmlkjihgfedcbaZYXWVUTSR…
Trypunosoma cruzi epimastigotes by DEAE-cellulose, phosphocellulose, and DNA agarose …
Trypunosoma cruzi epimastigotes by DEAE-cellulose, phosphocellulose, and DNA agarose …
Effect of polyamines on the activity of malarial α‐like DNA polymerase
U Bachrach, L ABU‐ELHEIGA - European journal of …, 1990 - Wiley Online Library
DNA polymerase from the malarial parasite Plasmodium falciparum required Mg2+ for
activity, Putrescine (1 mM) caused a twofold increase in enzyme activity in the presence of a …
activity, Putrescine (1 mM) caused a twofold increase in enzyme activity in the presence of a …
The molecular mechanism of inhibition of alpha-type DNA polymerases by N 2 -(butylphenyl)dGTP and 2-(butylanilino)dATP: variation in susceptibility to …
NN Khan, GE Wright, NC Brown - Nucleic acids research, 1991 - academic.oup.com
Calf thymus DNA polymerase alpha (pol α) and bacteriophage T4 DNA polymerase (pol T4)
were exploited as model enzymes to investigate the molecular mechanism of inhibitory …
were exploited as model enzymes to investigate the molecular mechanism of inhibitory …