STAT family of transcription factors in breast cancer: Pathogenesis and therapeutic opportunities and challenges
GL Wong, SG Manore, DL Doheny, HW Lo - Seminars in cancer biology, 2022 - Elsevier
Breast cancer is the most commonly diagnosed cancer and second-leading cause of cancer
deaths in women. Breast cancer stem cells (BCSCs) promote metastasis and therapeutic …
deaths in women. Breast cancer stem cells (BCSCs) promote metastasis and therapeutic …
[HTML][HTML] A review of biological targets and therapeutic approaches in the management of triple-negative breast cancer
Background Triple-negative breast cancer (TNBC) is a heterogeneous, aggressive
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …
phenotype of breast cancer with associated chemoresistance. The development of chemo-or …
Triple-negative breast cancer metastasis involves complex epithelial-mesenchymal transition dynamics and requires vimentin
Triple-negative breast cancer (TNBC) is an aggressive subtype associated with early
metastatic recurrence and worse patient outcomes. TNBC tumors express molecular …
metastatic recurrence and worse patient outcomes. TNBC tumors express molecular …
[HTML][HTML] Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis
K Li, X Sun, K Minami, K Tamari, K Ogawa, H Li… - Theranostics, 2023 - ncbi.nlm.nih.gov
Background: During a developmental process, embryos employ varying tactics to remove
unwanted cells. Using a procedure analogous to some of the embryonic cells, we generated …
unwanted cells. Using a procedure analogous to some of the embryonic cells, we generated …
A synchronized dual drug delivery molecule targeting cancer stem cells in tumor heterogeneity and metastasis
Cancer stem-like cells (CSCs) represent a key barrier to successful therapy for triple-
negative breast cancer (TNBC). CSCs promote the emergence of chemoresistance …
negative breast cancer (TNBC). CSCs promote the emergence of chemoresistance …
[HTML][HTML] The renaissance of CDK inhibitors in breast cancer therapy: An update on clinical trials and therapy resistance
M Abdelmalak, R Singh, M Anwer, P Ivanchenko… - Cancers, 2022 - mdpi.com
Simple Summary Cyclin-dependent kinase inhibitors (palbociclib (Ibrance), ribociclib
(Kisqali), and abemaciclib (Verzenio)), targeting aberrant cell-cycle activity have been …
(Kisqali), and abemaciclib (Verzenio)), targeting aberrant cell-cycle activity have been …
[HTML][HTML] Endorsement of TNBC biomarkers in precision therapy by nanotechnology
Simple Summary Triple-negative breast cancer (TNBC), the most aggressive and
heterogenous type of cancer, lacks the expression of hormones like estrogen, progesterone …
heterogenous type of cancer, lacks the expression of hormones like estrogen, progesterone …
[HTML][HTML] Predictive and prognostic role of peripheral blood T-cell subsets in triple-negative breast cancer
M Li, J Xu, C Jiang, J Zhang, T Sun - Frontiers in Oncology, 2022 - frontiersin.org
Background: Triple-negative breast cancer (TNBC), as a highly aggressive and metastatic
tumor, can still not contain the medical needs. It has become an urgent problem to develop …
tumor, can still not contain the medical needs. It has become an urgent problem to develop …
[HTML][HTML] Development of Cyclic Peptides Targeting the Epidermal Growth Factor Receptor in Mesenchymal Triple-Negative Breast Cancer Subtype
Triple-negative breast cancer (TNBC) is an aggressive malignancy characterized by the lack
of expression of estrogen and progesterone receptors and amplification of human epidermal …
of expression of estrogen and progesterone receptors and amplification of human epidermal …
[HTML][HTML] Correlation between the Warburg effect and progression of triple-negative breast cancer
S Liu, Y Li, M Yuan, Q Song, M Liu - Frontiers in Oncology, 2023 - frontiersin.org
Negative expression of the estrogen receptor, progesterone receptor, and human epidermal
growth factor receptor-2 disqualifies triple-negative breast cancer (TNBC) as a candidate for …
growth factor receptor-2 disqualifies triple-negative breast cancer (TNBC) as a candidate for …