RB family members are negative regulators of the cell cycle, involved in numerous biological
processes such as cellular senescence, development and differentiation. Disruption of RB …

DNA adenine methyltransferase (DAM) plays critical roles in diverse biological pathways in
gram‐negative bacteria, and specifically in regulating the expression of virulence genes in …

The IL-10 family of cytokines consists of 9 members, including the immune-regulatory IL-10;
Il19 is in close physical relationship with Il10 in the so-called IL-10 cytokine cluster on …

Finalist (teleological) implications have been described for both Darwinian and Lamarckian
theories, even though finalism appears to be more commonly associated with Lamarckism …

In vertebrates, androgens are essential in many biological functions, including reproduction,
immune system, metabolism, cardiovascular function, and the central nervous system. The …

Reduced DNA methylation has been reported in DICER1-deficient mouse ES cells.
Reductions seen at pericentric satellite repeats have suggested that siRNAs are required for …

Developmental epigenetics is a broad phenomenon, which was initially described by
Waddington as “the branch of biology which studies the causal interactions between genes …

Background During mammalian early embryogenesis, expression and epigenetic
heterogeneity emerge before the first cell fate determination, but the programs causing such …

Somatic nuclear transfer is a cloning technique that shows great promise in the application
to regenerative medicine. Although cloned animals are genetically identical to their donor …

Employing a new algorithm for identifying differentially methylated regions (DMRs) from
reduced representation bisulfite sequencing profiles, we identified 1972 hypermethylated …