Neurodegenerative diseases (NDDs) and neuropsychiatric disorders (NPDs) are two
common causes of death in elderly people, which includes progressive neuronal cell death …

DNMT1 is the main enzyme that uses the information on DNA methylation patterns in the
parent strand and methylates the daughter strand in freshly replicated hemimethylated DNA …

Schizophrenia (SZ) is a serious mental disorder that is typically treated with antipsychotic
medication. Treatment-resistant schizophrenia (TRS) is the condition where symptoms …

Aim: We tested the hypothesis that a subset of patients with autism spectrum disorder (ASD)
contains candidate genes with high DNA methylation differences (effective values) that …

Schizophrenia is a highly heritable neuropsychiatric disorder characterized by cognitive and
social dysfunction. Genetic, epigenetic, and environmental factors are together implicated in …

Data on schizophrenia (SZ), epilepsy (EPD) and bipolar disorders (BPD) suggested an
association of DNMT1 overexpression whereas certain variants of the gene were predicted …

Abstract Hereditary Sensory and Autonomic Neuropathy Type 1E (HSAN1E) is a rare
autosomal dominant neurological disorder due to missense mutations in DNA …

Early life stress (ELS) in the form of trauma or caregiver abuse and neglect is often
associated with psychopathology. However, not everyone exposed to ELS develops a …

Oral leukoplakia (OL), an oral potentially malignant disorder, begins with a hyperplastic/
hyperkeratotic stage at which no genome-scale somatic single nucleotide variant profiles …

Imperfect tandem repeats (TRs) of≥ 400nt are associated with 365 human 5'-genic CpG
islands (TR-CGIs). Most are clustered at chromosome ends, with a high density across …